Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 30 studies | 31% ± 12% | |
endothelial cell of lymphatic vessel | 15 studies | 40% ± 20% | |
smooth muscle cell | 9 studies | 19% ± 5% | |
basal cell | 9 studies | 37% ± 23% | |
endothelial cell of artery | 9 studies | 28% ± 13% | |
adipocyte | 8 studies | 23% ± 5% | |
fibroblast | 8 studies | 21% ± 4% | |
type I pneumocyte | 7 studies | 35% ± 12% | |
pericyte | 6 studies | 20% ± 3% | |
astrocyte | 6 studies | 32% ± 15% | |
epithelial cell | 6 studies | 40% ± 17% | |
club cell | 5 studies | 31% ± 11% | |
cardiac muscle cell | 4 studies | 27% ± 5% | |
ciliated cell | 4 studies | 31% ± 10% | |
endothelial cell of vascular tree | 4 studies | 39% ± 19% | |
capillary endothelial cell | 4 studies | 24% ± 8% | |
microglial cell | 4 studies | 25% ± 7% | |
mesothelial cell | 3 studies | 38% ± 11% | |
vein endothelial cell | 3 studies | 37% ± 19% | |
oligodendrocyte precursor cell | 3 studies | 28% ± 10% | |
myoepithelial cell | 3 studies | 35% ± 15% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 4723.24 | 1444 / 1445 | 98% | 17.56 | 180 / 183 |
ovary | 100% | 3632.86 | 180 / 180 | 98% | 12.91 | 420 / 430 |
skin | 100% | 8974.48 | 1809 / 1809 | 97% | 18.74 | 456 / 472 |
uterus | 100% | 5026.64 | 170 / 170 | 93% | 9.95 | 429 / 459 |
prostate | 100% | 3543.48 | 245 / 245 | 92% | 8.05 | 464 / 502 |
kidney | 100% | 3457.04 | 89 / 89 | 92% | 13.53 | 826 / 901 |
breast | 100% | 5506.65 | 458 / 459 | 91% | 11.74 | 1022 / 1118 |
lung | 99% | 3003.19 | 574 / 578 | 91% | 10.32 | 1050 / 1155 |
thymus | 100% | 2939.98 | 651 / 653 | 90% | 9.49 | 546 / 605 |
bladder | 100% | 3727.62 | 21 / 21 | 75% | 5.87 | 377 / 504 |
stomach | 97% | 2488.46 | 347 / 359 | 70% | 6.05 | 201 / 286 |
pancreas | 75% | 1236.71 | 245 / 328 | 91% | 7.69 | 162 / 178 |
intestine | 84% | 3384.01 | 809 / 966 | 54% | 3.78 | 286 / 527 |
adrenal gland | 100% | 5067.55 | 258 / 258 | 34% | 2.17 | 79 / 230 |
adipose | 100% | 4259.35 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 5533.94 | 1335 / 1335 | 0% | 0 | 0 / 0 |
muscle | 100% | 7383.53 | 803 / 803 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 4.41 | 1 / 1 |
brain | 40% | 507.54 | 1065 / 2642 | 56% | 3.29 | 395 / 705 |
eye | 0% | 0 | 0 / 0 | 95% | 7.90 | 76 / 80 |
spleen | 95% | 1559.32 | 228 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 93% | 11.93 | 42 / 45 |
heart | 93% | 2102.13 | 799 / 861 | 0% | 0 | 0 / 0 |
liver | 2% | 25.35 | 5 / 226 | 23% | 2.03 | 95 / 406 |
lymph node | 0% | 0 | 0 / 0 | 3% | 0.23 | 1 / 29 |
peripheral blood | 1% | 37.51 | 13 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0008285 | Biological process | negative regulation of cell population proliferation |
GO_0001946 | Biological process | lymphangiogenesis |
GO_0006470 | Biological process | protein dephosphorylation |
GO_0046825 | Biological process | regulation of protein export from nucleus |
GO_0005856 | Cellular component | cytoskeleton |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0004725 | Molecular function | protein tyrosine phosphatase activity |
GO_0005515 | Molecular function | protein binding |
GO_0030971 | Molecular function | receptor tyrosine kinase binding |
GO_0003712 | Molecular function | transcription coregulator activity |
Gene name | PTPN14 |
Protein name | Protein tyrosine phosphatase non-receptor type 14 (EC 3.1.3.48) PTPN14 protein Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez) |
Synonyms | PEZ PTPD2 |
Description | FUNCTION: Protein tyrosine phosphatase which may play a role in the regulation of lymphangiogenesis, cell-cell adhesion, cell-matrix adhesion, cell migration, cell growth and also regulates TGF-beta gene expression, thereby modulating epithelial-mesenchymal transition. Mediates beta-catenin dephosphorylation at adhesion junctions. Acts as a negative regulator of the oncogenic property of YAP, a downstream target of the hippo pathway, in a cell density-dependent manner. May function as a tumor suppressor. . |
Accessions | ENST00000366956.10 ENST00000543945.5 Q15678 E2J9M0 Q6PJC3 |