PRPS2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of PRPS2 at tissue level.

III. Associated gene sets

GO_0006139Biological processnucleobase-containing compound metabolic process
GO_0006015Biological process5-phosphoribose 1-diphosphate biosynthetic process
GO_0006164Biological processpurine nucleotide biosynthetic process
GO_0006098Biological processpentose-phosphate shunt
GO_0009156Biological processribonucleoside monophosphate biosynthetic process
GO_0005829Cellular componentcytosol
GO_0002189Cellular componentribose phosphate diphosphokinase complex
GO_0005737Cellular componentcytoplasm
GO_0042803Molecular functionprotein homodimerization activity
GO_0004749Molecular functionribose phosphate diphosphokinase activity
GO_0005524Molecular functionATP binding
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding
GO_0000287Molecular functionmagnesium ion binding
GO_0016301Molecular functionkinase activity

IV. Literature review

[source]
Gene namePRPS2
Protein namePhosphoribosyl pyrophosphate synthetase 2
Ribose-phosphate pyrophosphokinase 2 (EC 2.7.6.1) (PPRibP) (Phosphoribosyl pyrophosphate synthase II) (PRS-II)
Synonyms
DescriptionFUNCTION: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.

AccessionsENST00000461630.1
D3YTJ7
H7C540
P11908
A6NMS2
ENST00000398491.6 [P11908-2]
ENST00000489404.5
ENST00000380663.7
ENST00000380668.10 [P11908-1]