Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 25 studies | 33% ± 12% | |
| glutamatergic neuron | 8 studies | 50% ± 21% | |
| GABAergic neuron | 7 studies | 51% ± 21% | |
| epithelial cell | 7 studies | 38% ± 23% | |
| endothelial cell of lymphatic vessel | 7 studies | 42% ± 11% | |
| astrocyte | 6 studies | 32% ± 10% | |
| interneuron | 5 studies | 49% ± 25% | |
| cardiac muscle cell | 5 studies | 59% ± 15% | |
| basal cell | 5 studies | 38% ± 18% | |
| oligodendrocyte precursor cell | 5 studies | 25% ± 7% | |
| club cell | 5 studies | 32% ± 13% | |
| type I pneumocyte | 5 studies | 41% ± 11% | |
| type II pneumocyte | 5 studies | 44% ± 12% | |
| neuron | 4 studies | 26% ± 8% | |
| granule cell | 4 studies | 29% ± 15% | |
| vein endothelial cell | 4 studies | 31% ± 19% | |
| ciliated cell | 4 studies | 30% ± 8% | |
| GABAergic amacrine cell | 3 studies | 27% ± 5% | |
| amacrine cell | 3 studies | 29% ± 1% | |
| retinal cone cell | 3 studies | 23% ± 3% | |
| endothelial cell of vascular tree | 3 studies | 39% ± 15% | |
| hepatocyte | 3 studies | 31% ± 16% | |
| retinal pigment epithelial cell | 3 studies | 50% ± 15% | |
| respiratory goblet cell | 3 studies | 32% ± 13% | |
| fibroblast | 3 studies | 19% ± 2% | |
| lymphocyte | 3 studies | 19% ± 1% | |
| oligodendrocyte | 3 studies | 25% ± 8% | |
| mucus secreting cell | 3 studies | 29% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 3205.87 | 1445 / 1445 | 100% | 20.50 | 183 / 183 |
| prostate | 100% | 4979.80 | 245 / 245 | 100% | 26.64 | 502 / 502 |
| stomach | 100% | 3056.72 | 359 / 359 | 100% | 13.13 | 286 / 286 |
| intestine | 100% | 2640.25 | 966 / 966 | 100% | 13.29 | 526 / 527 |
| ovary | 100% | 2982.97 | 180 / 180 | 100% | 23.72 | 429 / 430 |
| pancreas | 100% | 2139.97 | 328 / 328 | 99% | 12.64 | 177 / 178 |
| breast | 100% | 2723.25 | 459 / 459 | 99% | 15.09 | 1108 / 1118 |
| bladder | 100% | 2852.71 | 21 / 21 | 99% | 12.25 | 499 / 504 |
| thymus | 100% | 10250.73 | 653 / 653 | 99% | 27.23 | 598 / 605 |
| lung | 100% | 3688.26 | 577 / 578 | 99% | 17.80 | 1143 / 1155 |
| uterus | 100% | 2407.21 | 170 / 170 | 98% | 15.02 | 449 / 459 |
| kidney | 100% | 2839.36 | 89 / 89 | 96% | 11.52 | 864 / 901 |
| adrenal gland | 100% | 1871.41 | 258 / 258 | 95% | 10.44 | 218 / 230 |
| brain | 97% | 3081.62 | 2556 / 2642 | 95% | 8.18 | 667 / 705 |
| liver | 100% | 1500.86 | 225 / 226 | 86% | 6.40 | 348 / 406 |
| skin | 78% | 3116.67 | 1413 / 1809 | 88% | 6.91 | 417 / 472 |
| spleen | 100% | 4544.76 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 14.90 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 15.14 | 1 / 1 |
| adipose | 100% | 2296.11 | 1200 / 1204 | 0% | 0 | 0 / 0 |
| heart | 100% | 4933.12 | 858 / 861 | 0% | 0 | 0 / 0 |
| muscle | 96% | 1322.82 | 770 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 95% | 1235.07 | 1266 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 89% | 5.73 | 71 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 83% | 5.12 | 24 / 29 |
| peripheral blood | 23% | 217.92 | 218 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0042981 | Biological process | regulation of apoptotic process |
| GO_0045786 | Biological process | negative regulation of cell cycle |
| GO_0072332 | Biological process | intrinsic apoptotic signaling pathway by p53 class mediator |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0048471 | Cellular component | perinuclear region of cytoplasm |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0005515 | Molecular function | protein binding |
| GO_0002039 | Molecular function | p53 binding |
| Gene name | PPP1R13B |
| Protein name | Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B) Protein phosphatase 1 regulatory subunit 13B Alternative protein PPP1R13B |
| Synonyms | ASPP1 KIAA0771 |
| Description | FUNCTION: Regulator that plays a central role in regulation of apoptosis via its interaction with p53/TP53 . Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. . |
| Accessions | ENST00000557082.5 A0A3B3ISJ2 ENST00000556597.1 ENST00000553739.2 H0YJG1 ENST00000555734.5 ENST00000647748.1 G3V5J1 Q96KQ4 G3V3S2 ENST00000557587.1 L8EAS9 G3V2L3 ENST00000202556.14 H0YJL1 |