Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 12 studies | 60% ± 23% | |
| oligodendrocyte precursor cell | 11 studies | 35% ± 12% | |
| GABAergic neuron | 10 studies | 59% ± 24% | |
| astrocyte | 9 studies | 33% ± 16% | |
| interneuron | 6 studies | 65% ± 20% | |
| retina horizontal cell | 6 studies | 60% ± 29% | |
| retinal cone cell | 6 studies | 66% ± 33% | |
| neuron | 5 studies | 41% ± 20% | |
| endothelial cell | 5 studies | 44% ± 13% | |
| granule cell | 4 studies | 53% ± 26% | |
| amacrine cell | 4 studies | 42% ± 9% | |
| retinal ganglion cell | 4 studies | 49% ± 16% | |
| retinal rod cell | 4 studies | 41% ± 5% | |
| ciliated cell | 4 studies | 34% ± 7% | |
| oligodendrocyte | 4 studies | 37% ± 14% | |
| GABAergic interneuron | 3 studies | 59% ± 2% | |
| GABAergic amacrine cell | 3 studies | 43% ± 8% | |
| OFF-bipolar cell | 3 studies | 37% ± 14% | |
| glycinergic amacrine cell | 3 studies | 34% ± 9% | |
| rod bipolar cell | 3 studies | 64% ± 29% | |
| ependymal cell | 3 studies | 41% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 96% | 1242.26 | 2549 / 2642 | 99% | 13.97 | 699 / 705 |
| adrenal gland | 100% | 1283.15 | 258 / 258 | 95% | 9.11 | 218 / 230 |
| prostate | 61% | 227.70 | 150 / 245 | 95% | 10.05 | 475 / 502 |
| kidney | 30% | 71.20 | 27 / 89 | 29% | 1.48 | 262 / 901 |
| liver | 32% | 62.31 | 73 / 226 | 22% | 0.89 | 89 / 406 |
| skin | 0% | 0.56 | 7 / 1809 | 39% | 1.19 | 183 / 472 |
| breast | 8% | 13.09 | 38 / 459 | 28% | 1.50 | 312 / 1118 |
| heart | 35% | 93.87 | 300 / 861 | 0% | 0 | 0 / 0 |
| uterus | 13% | 23.02 | 22 / 170 | 17% | 0.82 | 80 / 459 |
| pancreas | 9% | 14.40 | 31 / 328 | 20% | 0.65 | 36 / 178 |
| ovary | 12% | 16.46 | 22 / 180 | 16% | 0.38 | 69 / 430 |
| lung | 12% | 18.46 | 67 / 578 | 16% | 0.59 | 181 / 1155 |
| stomach | 13% | 17.93 | 45 / 359 | 12% | 0.41 | 35 / 286 |
| eye | 0% | 0 | 0 / 0 | 23% | 0.57 | 18 / 80 |
| esophagus | 10% | 13.34 | 139 / 1445 | 9% | 0.40 | 16 / 183 |
| lymph node | 0% | 0 | 0 / 0 | 17% | 0.66 | 5 / 29 |
| spleen | 12% | 15.97 | 30 / 241 | 0% | 0 | 0 / 0 |
| bladder | 0% | 0 | 0 / 21 | 9% | 0.39 | 44 / 504 |
| intestine | 4% | 5.75 | 39 / 966 | 5% | 0.16 | 24 / 527 |
| thymus | 6% | 6.91 | 36 / 653 | 2% | 0.04 | 11 / 605 |
| tonsil | 0% | 0 | 0 / 0 | 7% | 0.37 | 3 / 45 |
| adipose | 6% | 8.70 | 78 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 1% | 1.59 | 11 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0.34 | 2 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0071222 | Biological process | cellular response to lipopolysaccharide |
| GO_0051496 | Biological process | positive regulation of stress fiber assembly |
| GO_0035970 | Biological process | peptidyl-threonine dephosphorylation |
| GO_0071466 | Biological process | cellular response to xenobiotic stimulus |
| GO_0006469 | Biological process | negative regulation of protein kinase activity |
| GO_0006470 | Biological process | protein dephosphorylation |
| GO_0005730 | Cellular component | nucleolus |
| GO_0032991 | Cellular component | protein-containing complex |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0005515 | Molecular function | protein binding |
| GO_0017018 | Molecular function | myosin phosphatase activity |
| GO_0004722 | Molecular function | protein serine/threonine phosphatase activity |
| GO_0046872 | Molecular function | metal ion binding |
| Gene name | PPM1E |
| Protein name | Protein phosphatase 1E (EC 3.1.3.16) (Ca(2+)/calmodulin-dependent protein kinase phosphatase N) (CaMKP-N) (CaMKP-nucleus) (CaMKN) (Partner of PIX 1) (Partner of PIX-alpha) (Partner of PIXA) |
| Synonyms | KIAA1072 POPX1 CAMKN |
| Description | FUNCTION: Protein phosphatase that inactivates multifunctional CaM kinases such as CAMK4 and CAMK2 (By similarity). Dephosphorylates and inactivates PAK. May play a role in the inhibition of actin fiber stress breakdown and in morphological changes driven by TNK2/CDC42. Dephosphorylates PRKAA2 (By similarity). . |
| Accessions | ENST00000308249.4 [Q8WY54-2] Q8WY54 |