POU3F4 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of POU3F4 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of POU3F4 at tissue level.

III. Associated gene sets

GO_0007420Biological processbrain development
GO_0007605Biological processsensory perception of sound
GO_2001054Biological processnegative regulation of mesenchymal cell apoptotic process
GO_0090103Biological processcochlea morphogenesis
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene namePOU3F4
Protein namePOU domain, class 3, transcription factor 4 (Brain-specific homeobox/POU domain protein 4) (Brain-4) (Brn-4) (Octamer-binding protein 9) (Oct-9) (Octamer-binding transcription factor 9) (OTF-9)
POU domain protein
SynonymsOTF9
BRN4
DescriptionFUNCTION: Probable transcription factor which exert its primary action widely during early neural development and in a very limited set of neurons in the mature brain.

AccessionsA0A2R8Y739
P49335
ENST00000644024.2