PON2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0009636Biological processresponse to toxic substance
GO_1901335Biological processlactone catabolic process
GO_0005576Cellular componentextracellular region
GO_0005886Cellular componentplasma membrane
GO_0042803Molecular functionprotein homodimerization activity
GO_0102007Molecular functionacyl-L-homoserine-lactone lactonohydrolase activity
GO_0046872Molecular functionmetal ion binding
GO_0004064Molecular functionarylesterase activity

IV. Literature review

[source]
Gene namePON2
Protein nameParaoxonase 2
Serum paraoxonase/arylesterase 2 (PON 2) (EC 3.1.1.2) (EC 3.1.1.81) (Aromatic esterase 2) (A-esterase 2) (Serum aryldialkylphosphatase 2)
Paraoxonase (EC 3.1.1.2)
SynonymshCG_1640820
DescriptionFUNCTION: Capable of hydrolyzing lactones and a number of aromatic carboxylic acid esters. Has antioxidant activity. Is not associated with high density lipoprotein. Prevents LDL lipid peroxidation, reverses the oxidation of mildly oxidized LDL, and inhibits the ability of MM-LDL to induce monocyte chemotaxis. .

AccessionsENST00000455123.5
ENST00000632034.1
ENST00000483292.5
ENST00000493290.5
ENST00000478801.5
ENST00000490778.5
G3XAK4
A0A2Q2SAK4
ENST00000222572.8 [Q15165-2]
A0A0J9YXU7
A0A0J9YYF3
ENST00000469926.5
ENST00000633192.1
ENST00000491069.5
ENST00000633531.1 [Q15165-2]
Q6PJZ2
ENST00000433091.6 [Q15165-3]
A0A0J9YXM1
ENST00000446142.5
A0A0J9YVW3
A0A0J9YXF2
Q15165
A0A0J9YYJ1
A0A0J9YYF0