Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 21 studies | 29% ± 11% | |
oligodendrocyte | 13 studies | 35% ± 14% | |
fibroblast | 12 studies | 24% ± 8% | |
microglial cell | 11 studies | 30% ± 12% | |
astrocyte | 11 studies | 34% ± 16% | |
GABAergic neuron | 8 studies | 35% ± 20% | |
glutamatergic neuron | 8 studies | 39% ± 26% | |
macrophage | 8 studies | 32% ± 12% | |
adipocyte | 8 studies | 28% ± 7% | |
oligodendrocyte precursor cell | 8 studies | 33% ± 15% | |
dendritic cell | 7 studies | 24% ± 9% | |
pericyte | 7 studies | 23% ± 9% | |
endothelial cell of lymphatic vessel | 7 studies | 29% ± 11% | |
interneuron | 6 studies | 36% ± 22% | |
mast cell | 6 studies | 26% ± 6% | |
type I pneumocyte | 6 studies | 22% ± 6% | |
neuron | 5 studies | 29% ± 16% | |
B cell | 5 studies | 21% ± 4% | |
myeloid cell | 5 studies | 22% ± 3% | |
epithelial cell | 5 studies | 30% ± 8% | |
lymphocyte | 5 studies | 19% ± 5% | |
type II pneumocyte | 5 studies | 19% ± 5% | |
non-classical monocyte | 4 studies | 24% ± 9% | |
capillary endothelial cell | 4 studies | 18% ± 2% | |
cardiac muscle cell | 4 studies | 17% ± 1% | |
monocyte | 4 studies | 24% ± 6% | |
smooth muscle cell | 4 studies | 22% ± 4% | |
plasmacytoid dendritic cell | 4 studies | 24% ± 6% | |
classical monocyte | 3 studies | 27% ± 4% | |
hematopoietic precursor cell | 3 studies | 22% ± 7% | |
GABAergic interneuron | 3 studies | 18% ± 3% | |
glial cell | 3 studies | 24% ± 3% | |
mononuclear phagocyte | 3 studies | 21% ± 4% | |
vein endothelial cell | 3 studies | 32% ± 19% | |
ciliated cell | 3 studies | 22% ± 2% | |
ependymal cell | 3 studies | 28% ± 16% | |
myofibroblast cell | 3 studies | 20% ± 4% | |
alveolar macrophage | 3 studies | 24% ± 7% | |
basal cell | 3 studies | 30% ± 15% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 1234.11 | 1443 / 1445 | 99% | 6.59 | 182 / 183 |
brain | 99% | 920.50 | 2622 / 2642 | 98% | 6.74 | 691 / 705 |
lung | 100% | 1528.37 | 578 / 578 | 97% | 6.07 | 1122 / 1155 |
thymus | 100% | 1895.26 | 653 / 653 | 97% | 9.17 | 587 / 605 |
breast | 100% | 1695.58 | 459 / 459 | 95% | 8.21 | 1065 / 1118 |
adrenal gland | 100% | 1602.96 | 258 / 258 | 95% | 7.21 | 218 / 230 |
kidney | 100% | 973.80 | 89 / 89 | 93% | 8.42 | 835 / 901 |
prostate | 100% | 1295.41 | 245 / 245 | 92% | 6.11 | 463 / 502 |
stomach | 100% | 986.83 | 359 / 359 | 92% | 5.08 | 263 / 286 |
pancreas | 100% | 723.97 | 327 / 328 | 92% | 5.34 | 164 / 178 |
intestine | 100% | 1297.51 | 965 / 966 | 88% | 4.32 | 465 / 527 |
uterus | 100% | 1782.81 | 170 / 170 | 87% | 4.33 | 400 / 459 |
skin | 100% | 1302.96 | 1803 / 1809 | 84% | 6.67 | 398 / 472 |
ovary | 100% | 1706.64 | 180 / 180 | 81% | 3.24 | 350 / 430 |
bladder | 100% | 1453.86 | 21 / 21 | 79% | 3.74 | 396 / 504 |
liver | 100% | 651.00 | 225 / 226 | 67% | 2.97 | 272 / 406 |
blood vessel | 100% | 1881.84 | 1335 / 1335 | 0% | 0 | 0 / 0 |
muscle | 100% | 1074.23 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 1156.10 | 241 / 241 | 0% | 0 | 0 / 0 |
adipose | 100% | 1816.48 | 1203 / 1204 | 0% | 0 | 0 / 0 |
heart | 96% | 851.32 | 830 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 80% | 4.76 | 36 / 45 |
peripheral blood | 67% | 1089.79 | 619 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 66% | 4.27 | 19 / 29 |
eye | 0% | 0 | 0 / 0 | 45% | 1.98 | 36 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006974 | Biological process | DNA damage response |
GO_0006281 | Biological process | DNA repair |
GO_0006297 | Biological process | nucleotide-excision repair, DNA gap filling |
GO_0006260 | Biological process | DNA replication |
GO_0042276 | Biological process | error-prone translesion synthesis |
GO_0034644 | Biological process | cellular response to UV |
GO_0090734 | Cellular component | site of DNA damage |
GO_0016604 | Cellular component | nuclear body |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0003887 | Molecular function | DNA-directed DNA polymerase activity |
GO_0046872 | Molecular function | metal ion binding |
GO_0003684 | Molecular function | damaged DNA binding |
Gene name | POLK |
Protein name | DNA polymerase kappa DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP) Alternative protein POLK |
Synonyms | hCG_18353 DINB1 |
Description | FUNCTION: DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Depending on the context, it inserts the correct base, but causes frequent base transitions, transversions and frameshifts. Lacks 3'-5' proofreading exonuclease activity. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity. . |
Accessions | D6RAE5 ENST00000241436.9 [Q9UBT6-1] D6RAI7 ENST00000510815.6 [Q9UBT6-4] ENST00000514141.5 ENST00000511527.5 L8E8A5 ENST00000505975.5 ENST00000504026.5 [Q9UBT6-6] ENST00000514296.5 ENST00000503479.6 D6RDX9 Q9UBT6 ENST00000509126.2 [Q9UBT6-5] ENST00000515295.5 [Q9UBT6-2] D6R9M8 ENST00000508526.5 [Q9UBT6-3] ENST00000505774.5 |