Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 28 studies | 35% ± 14% | |
| astrocyte | 12 studies | 41% ± 14% | |
| glutamatergic neuron | 11 studies | 49% ± 22% | |
| capillary endothelial cell | 11 studies | 23% ± 9% | |
| endothelial cell of artery | 10 studies | 30% ± 14% | |
| type I pneumocyte | 8 studies | 31% ± 11% | |
| macrophage | 7 studies | 21% ± 7% | |
| oligodendrocyte precursor cell | 7 studies | 23% ± 5% | |
| endothelial cell of lymphatic vessel | 7 studies | 33% ± 7% | |
| GABAergic neuron | 7 studies | 41% ± 19% | |
| neuron | 6 studies | 42% ± 9% | |
| epithelial cell | 6 studies | 36% ± 25% | |
| interneuron | 6 studies | 46% ± 16% | |
| retina horizontal cell | 6 studies | 62% ± 16% | |
| ciliated cell | 6 studies | 22% ± 8% | |
| basal cell | 6 studies | 42% ± 20% | |
| type II pneumocyte | 6 studies | 30% ± 10% | |
| fibroblast | 6 studies | 22% ± 4% | |
| endothelial cell of vascular tree | 5 studies | 32% ± 16% | |
| smooth muscle cell | 5 studies | 22% ± 4% | |
| granule cell | 4 studies | 37% ± 4% | |
| amacrine cell | 4 studies | 36% ± 16% | |
| vein endothelial cell | 4 studies | 27% ± 11% | |
| club cell | 4 studies | 28% ± 4% | |
| pericyte | 3 studies | 19% ± 4% | |
| GABAergic interneuron | 3 studies | 30% ± 10% | |
| GABAergic amacrine cell | 3 studies | 30% ± 11% | |
| glycinergic amacrine cell | 3 studies | 32% ± 8% | |
| ependymal cell | 3 studies | 29% ± 12% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| pancreas | 100% | 12180.25 | 328 / 328 | 100% | 19.61 | 178 / 178 |
| esophagus | 100% | 6301.88 | 1445 / 1445 | 99% | 27.84 | 182 / 183 |
| thymus | 100% | 5238.28 | 652 / 653 | 99% | 23.74 | 598 / 605 |
| stomach | 100% | 4133.66 | 359 / 359 | 99% | 16.71 | 282 / 286 |
| intestine | 100% | 3862.02 | 966 / 966 | 98% | 15.16 | 515 / 527 |
| bladder | 100% | 6458.38 | 21 / 21 | 95% | 13.63 | 477 / 504 |
| uterus | 100% | 4474.41 | 170 / 170 | 94% | 16.33 | 430 / 459 |
| lung | 100% | 10743.40 | 578 / 578 | 94% | 16.51 | 1081 / 1155 |
| brain | 94% | 4966.15 | 2481 / 2642 | 98% | 15.26 | 694 / 705 |
| ovary | 100% | 8671.02 | 180 / 180 | 87% | 10.00 | 375 / 430 |
| breast | 99% | 3512.60 | 455 / 459 | 85% | 7.73 | 949 / 1118 |
| kidney | 93% | 1855.28 | 83 / 89 | 83% | 12.69 | 751 / 901 |
| skin | 96% | 5458.39 | 1744 / 1809 | 79% | 10.16 | 372 / 472 |
| prostate | 100% | 3347.01 | 244 / 245 | 75% | 4.60 | 375 / 502 |
| liver | 52% | 693.73 | 117 / 226 | 80% | 5.68 | 325 / 406 |
| adrenal gland | 24% | 336.88 | 63 / 258 | 77% | 15.20 | 178 / 230 |
| blood vessel | 100% | 5695.14 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 100% | 4769.72 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 99% | 3470.78 | 798 / 803 | 0% | 0 | 0 / 0 |
| heart | 99% | 3374.40 | 852 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 18.84 | 43 / 45 |
| eye | 0% | 0 | 0 / 0 | 90% | 14.04 | 72 / 80 |
| spleen | 51% | 670.45 | 122 / 241 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 7% | 0.29 | 2 / 29 |
| peripheral blood | 6% | 75.67 | 55 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0008360 | Biological process | regulation of cell shape |
| GO_0051642 | Biological process | centrosome localization |
| GO_0007162 | Biological process | negative regulation of cell adhesion |
| GO_0071526 | Biological process | semaphorin-plexin signaling pathway |
| GO_0021935 | Biological process | cerebellar granule cell precursor tangential migration |
| GO_0043087 | Biological process | regulation of GTPase activity |
| GO_0050772 | Biological process | positive regulation of axonogenesis |
| GO_0021915 | Biological process | neural tube development |
| GO_0030334 | Biological process | regulation of cell migration |
| GO_0060174 | Biological process | limb bud formation |
| GO_0001756 | Biological process | somitogenesis |
| GO_0060037 | Biological process | pharyngeal system development |
| GO_0002116 | Cellular component | semaphorin receptor complex |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0017154 | Molecular function | semaphorin receptor activity |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | PLXNA2 |
| Protein name | Plexin-A2 (Semaphorin receptor OCT) |
| Synonyms | PLXN2 KIAA0463 UNQ209/PRO235 OCT |
| Description | FUNCTION: Coreceptor for SEMA3A and SEMA6A. Necessary for signaling by SEMA6A and class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (By similarity). . |
| Accessions | O75051 ENST00000367033.4 [O75051-1] |