PLP1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006954Biological processinflammatory response
GO_0061564Biological processaxon development
GO_0010628Biological processpositive regulation of gene expression
GO_1904427Biological processpositive regulation of calcium ion transmembrane transport
GO_0022010Biological processcentral nervous system myelination
GO_0098990Biological processAMPA selective glutamate receptor signaling pathway
GO_0030335Biological processpositive regulation of cell migration
GO_0007268Biological processchemical synaptic transmission
GO_0008366Biological processaxon ensheathment
GO_0021762Biological processsubstantia nigra development
GO_0042759Biological processlong-chain fatty acid biosynthetic process
GO_0014002Biological processastrocyte development
GO_0034683Cellular componentintegrin alphav-beta3 complex
GO_0043209Cellular componentmyelin sheath
GO_0005886Cellular componentplasma membrane
GO_0045202Cellular componentsynapse
GO_0044877Molecular functionprotein-containing complex binding
GO_0019911Molecular functionstructural constituent of myelin sheath
GO_0005198Molecular functionstructural molecule activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene namePLP1
Protein nameMyelin proteolipid protein (PLP) (Lipophilin)
Myelin proteolipid protein (Lipophilin)
SynonymsPLP
hCG_17970
DescriptionFUNCTION: This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin.

FUNCTION: This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin. .

FUNCTION: This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin. .

FUNCTION: This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin. .

FUNCTION: This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin. .

FUNCTION: This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin. .

FUNCTION: This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin. .

FUNCTION: This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin. .

AccessionsENST00000455268.5
B1B1G2
B1B1G3
A0A0S2Z4D4
ENST00000612423.4 [P60201-1]
A8K9L3
ENST00000434483.5
B1B1G4
B1B1G6
ENST00000422393.5
P60201
ENST00000443502.5
ENST00000619236.1 [P60201-2]
B1B1G1
ENST00000621218.5 [P60201-1]
ENST00000433491.5
ENST00000494475.5