Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte | 16 studies | 78% ± 19% | |
pericyte | 16 studies | 42% ± 22% | |
endothelial cell | 12 studies | 42% ± 16% | |
oligodendrocyte precursor cell | 12 studies | 41% ± 15% | |
smooth muscle cell | 12 studies | 40% ± 22% | |
glutamatergic neuron | 11 studies | 54% ± 23% | |
mast cell | 11 studies | 47% ± 15% | |
GABAergic neuron | 10 studies | 36% ± 18% | |
microglial cell | 10 studies | 36% ± 21% | |
macrophage | 9 studies | 28% ± 8% | |
fibroblast | 9 studies | 30% ± 15% | |
astrocyte | 7 studies | 38% ± 23% | |
adipocyte | 7 studies | 29% ± 5% | |
interneuron | 6 studies | 44% ± 14% | |
cardiac muscle cell | 6 studies | 73% ± 20% | |
mesothelial cell | 6 studies | 56% ± 26% | |
neuron | 5 studies | 42% ± 10% | |
type I pneumocyte | 5 studies | 35% ± 6% | |
granule cell | 4 studies | 43% ± 28% | |
amacrine cell | 4 studies | 45% ± 31% | |
retinal pigment epithelial cell | 4 studies | 44% ± 18% | |
retina horizontal cell | 4 studies | 44% ± 14% | |
regulatory T cell | 4 studies | 38% ± 10% | |
monocyte | 4 studies | 18% ± 2% | |
GABAergic interneuron | 3 studies | 29% ± 3% | |
GABAergic amacrine cell | 3 studies | 39% ± 14% | |
glycinergic amacrine cell | 3 studies | 33% ± 8% | |
basal cell | 3 studies | 38% ± 13% | |
endothelial cell of vascular tree | 3 studies | 35% ± 14% | |
myeloid cell | 3 studies | 32% ± 12% | |
T cell | 3 studies | 23% ± 0% | |
alveolar macrophage | 3 studies | 18% ± 4% | |
club cell | 3 studies | 43% ± 23% | |
lymphocyte | 3 studies | 28% ± 11% | |
leukocyte | 3 studies | 33% ± 13% | |
kidney distal convoluted tubule epithelial cell | 3 studies | 65% ± 28% | |
kidney loop of Henle epithelial cell | 3 studies | 62% ± 31% | |
renal alpha-intercalated cell | 3 studies | 70% ± 36% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 98% | 2234.85 | 2581 / 2642 | 91% | 10.81 | 645 / 705 |
kidney | 100% | 1830.01 | 89 / 89 | 79% | 7.62 | 712 / 901 |
breast | 95% | 716.61 | 436 / 459 | 69% | 6.36 | 769 / 1118 |
thymus | 96% | 766.53 | 629 / 653 | 61% | 3.26 | 367 / 605 |
prostate | 86% | 1058.88 | 210 / 245 | 66% | 3.88 | 332 / 502 |
adrenal gland | 82% | 735.11 | 212 / 258 | 65% | 6.10 | 150 / 230 |
ovary | 98% | 1276.81 | 177 / 180 | 18% | 0.64 | 77 / 430 |
uterus | 90% | 2122.48 | 153 / 170 | 19% | 1.60 | 85 / 459 |
lung | 81% | 474.57 | 466 / 578 | 27% | 1.05 | 312 / 1155 |
esophagus | 66% | 1835.40 | 956 / 1445 | 35% | 1.48 | 64 / 183 |
blood vessel | 100% | 2451.71 | 1332 / 1335 | 0% | 0 | 0 / 0 |
muscle | 99% | 1692.62 | 795 / 803 | 0% | 0 | 0 / 0 |
adipose | 97% | 1009.97 | 1172 / 1204 | 0% | 0 | 0 / 0 |
heart | 96% | 3287.75 | 827 / 861 | 0% | 0 | 0 / 0 |
intestine | 75% | 830.51 | 727 / 966 | 14% | 0.46 | 74 / 527 |
stomach | 58% | 494.68 | 207 / 359 | 27% | 1.07 | 77 / 286 |
bladder | 71% | 1098.00 | 15 / 21 | 10% | 0.44 | 51 / 504 |
skin | 24% | 127.43 | 436 / 1809 | 57% | 3.96 | 268 / 472 |
lymph node | 0% | 0 | 0 / 0 | 38% | 1.75 | 11 / 29 |
tonsil | 0% | 0 | 0 / 0 | 29% | 0.91 | 13 / 45 |
pancreas | 1% | 3.21 | 3 / 328 | 25% | 0.74 | 45 / 178 |
peripheral blood | 17% | 93.49 | 161 / 929 | 0% | 0 | 0 / 0 |
spleen | 12% | 49.31 | 30 / 241 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 5% | 0.14 | 4 / 80 |
liver | 0% | 0 | 0 / 226 | 4% | 0.14 | 16 / 406 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007214 | Biological process | gamma-aminobutyric acid signaling pathway |
GO_0032228 | Biological process | regulation of synaptic transmission, GABAergic |
GO_0035556 | Biological process | intracellular signal transduction |
GO_0120163 | Biological process | negative regulation of cold-induced thermogenesis |
GO_0006629 | Biological process | lipid metabolic process |
GO_0005737 | Cellular component | cytoplasm |
GO_0004629 | Molecular function | phospholipase C activity |
GO_0004435 | Molecular function | phosphatidylinositol phospholipase C activity |
Gene name | PLCL1 |
Protein name | Inactive phospholipase C-like protein 1 (PLC-L1) (Phospholipase C-deleted in lung carcinoma) (Phospholipase C-related but catalytically inactive protein) (PRIP) Phosphoinositide phospholipase C (EC 3.1.4.11) Phospholipase C like 1 (inactive) |
Synonyms | |
Description | FUNCTION: Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol. Component in the phospho-dependent endocytosis process of GABA A receptor (By similarity). Regulates the turnover of receptors and thus contributes to the maintenance of GABA-mediated synaptic inhibition. Its aberrant expression could contribute to the genesis and progression of lung carcinoma. Acts as an inhibitor of PPP1C. . |
Accessions | ENST00000435320.1 ENST00000428675.6 [Q15111-1] F8WAR2 ENST00000487695.6 Q15111 H3BUD4 |