I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| retinal rod cell | 6 studies | 21% ± 2% | |
| retinal bipolar neuron | 3 studies | 21% ± 2% | |
| retinal ganglion cell | 3 studies | 37% ± 14% | |
| basal cell | 3 studies | 22% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| retinal rod cell | 6 studies | 21% ± 2% | |
| retinal bipolar neuron | 3 studies | 21% ± 2% | |
| retinal ganglion cell | 3 studies | 37% ± 14% | |
| basal cell | 3 studies | 22% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| eye | 3 studies | 19% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 88% | 6333.79 | 216 / 245 | 87% | 6.52 | 438 / 502 |
| brain | 92% | 7051.87 | 2418 / 2642 | 71% | 5.46 | 502 / 705 |
| pancreas | 48% | 1091.36 | 158 / 328 | 75% | 6.05 | 133 / 178 |
| bladder | 52% | 2922.00 | 11 / 21 | 59% | 9.38 | 295 / 504 |
| esophagus | 39% | 2349.52 | 557 / 1445 | 65% | 8.73 | 119 / 183 |
| thymus | 39% | 870.88 | 256 / 653 | 61% | 4.35 | 372 / 605 |
| kidney | 58% | 1378.51 | 52 / 89 | 42% | 2.83 | 377 / 901 |
| ureter | 0% | 0 | 0 / 0 | 100% | 4.32 | 1 / 1 |
| breast | 54% | 2133.51 | 249 / 459 | 43% | 2.26 | 483 / 1118 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 20.53 | 43 / 45 |
| adrenal gland | 27% | 762.14 | 69 / 258 | 65% | 28.09 | 150 / 230 |
| spleen | 84% | 1957.11 | 202 / 241 | 0% | 0 | 0 / 0 |
| skin | 72% | 11063.19 | 1305 / 1809 | 11% | 0.56 | 50 / 472 |
| liver | 48% | 1118.56 | 109 / 226 | 28% | 2.47 | 112 / 406 |
| uterus | 4% | 138.23 | 6 / 170 | 66% | 12.95 | 305 / 459 |
| lung | 18% | 299.92 | 102 / 578 | 52% | 6.08 | 602 / 1155 |
| intestine | 13% | 297.14 | 128 / 966 | 26% | 1.63 | 139 / 527 |
| lymph node | 0% | 0 | 0 / 0 | 38% | 1.39 | 11 / 29 |
| peripheral blood | 29% | 628.09 | 265 / 929 | 0% | 0 | 0 / 0 |
| stomach | 1% | 10.83 | 3 / 359 | 17% | 0.85 | 48 / 286 |
| ovary | 0% | 0 | 0 / 180 | 10% | 0.59 | 45 / 430 |
| eye | 0% | 0 | 0 / 0 | 6% | 1.22 | 5 / 80 |
| adipose | 1% | 22.04 | 14 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 1% | 12.95 | 7 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 0% | 2.04 | 1 / 803 | 0% | 0 | 0 / 0 |
| heart | 0% | 1.38 | 1 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0046488 | Biological process | phosphatidylinositol metabolic process |
| GO_0007200 | Biological process | phospholipase C-activating G protein-coupled receptor signaling pathway |
| GO_0051209 | Biological process | release of sequestered calcium ion into cytosol |
| GO_0048015 | Biological process | phosphatidylinositol-mediated signaling |
| GO_0016042 | Biological process | lipid catabolic process |
| GO_0005575 | Cellular component | cellular_component |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005509 | Molecular function | calcium ion binding |
| GO_0004435 | Molecular function | phosphatidylinositol phospholipase C activity |
| Gene name | PLCH2 |
| Protein name | PLCH2 protein Phospholipase C eta 2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-eta-2) (Phosphoinositide phospholipase C-like 4) (PLC-L4) (Phospholipase C-like protein 4) (Phospholipase C-eta-2) (PLC-eta2) Phosphoinositide phospholipase C (EC 3.1.4.11) |
| Synonyms | PLCL4 KIAA0450 |
| Description | FUNCTION: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes . This phospholipase activity is very sensitive to calcium. May be important for formation and maintenance of the neuronal network in the postnatal brain (By similarity). . |
| Accessions | ENST00000419816.6 [O75038-1] ENST00000620687.1 [O75038-1] B9DI82 ENST00000609981.5 ENST00000378486.8 [O75038-1] O75038 ENST00000449969.5 [O75038-2] V9GY64 ENST00000626246.2 [O75038-1] ENST00000278878.6 ENST00000627854.2 [O75038-2] A2VCM4 |
