PDHA1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006086Biological processacetyl-CoA biosynthetic process from pyruvate
GO_0006006Biological processglucose metabolic process
GO_0006099Biological processtricarboxylic acid cycle
GO_0005730Cellular componentnucleolus
GO_0045254Cellular componentpyruvate dehydrogenase complex
GO_0005759Cellular componentmitochondrial matrix
GO_0005739Cellular componentmitochondrion
GO_0005634Cellular componentnucleus
GO_0034604Molecular functionpyruvate dehydrogenase (NAD+) activity
GO_0005515Molecular functionprotein binding
GO_0004739Molecular functionpyruvate dehydrogenase (acetyl-transferring) activity

IV. Literature review

[source]
Gene namePDHA1
Protein namePyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (EC 1.2.4.1) (PDHE1-A type I)
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
PDHA1 (EC 1.2.4.1)
Pyruvate dehydrogenase E1 subunit alpha 1
Pyruvate dehydrogenase E1 component subunit alpha (EC 1.2.4.1)
Pyruvate dehydrogenase E1-alpha-subunit
Pyruvate dehydrogenase alpha subunit
SynonymsPHE1A
DescriptionFUNCTION: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. .

FUNCTION: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. .

AccessionsENST00000422285.7 [P08559-1]
Q6LCA3
ENST00000696704.1
ENST00000423505.6 [P08559-4]
ENST00000540249.5 [P08559-3]
ENST00000355808.10 [P08559-2]
Q5JPU2
A5YPB6
A0A8Q3WLK5
Q99724
P78557
Q5JPU1
Q5JPT9
Q99725
A0A8Q3WLI8
ENST00000423505.5
ENST00000417819.6
ENST00000379805.4
Q5JPU0
ENST00000696705.1
P08559
Q9UNV7
ENST00000355808.9