Name | Number of supported studies | Average coverage | |
---|---|---|---|
kidney loop of Henle epithelial cell | 6 studies | 32% ± 10% | |
endothelial cell | 6 studies | 22% ± 6% | |
fibroblast | 6 studies | 21% ± 6% | |
epithelial cell | 6 studies | 41% ± 11% | |
epithelial cell of proximal tubule | 5 studies | 18% ± 3% | |
renal alpha-intercalated cell | 4 studies | 39% ± 5% | |
smooth muscle cell | 4 studies | 19% ± 2% | |
natural killer cell | 4 studies | 20% ± 4% | |
erythroblast | 4 studies | 37% ± 15% | |
erythrocyte | 4 studies | 29% ± 16% | |
basal cell | 4 studies | 31% ± 13% | |
plasmablast | 3 studies | 50% ± 14% | |
ionocyte | 3 studies | 22% ± 4% | |
pancreatic A cell | 3 studies | 26% ± 8% | |
conventional dendritic cell | 3 studies | 28% ± 10% | |
hematopoietic precursor cell | 3 studies | 23% ± 5% | |
non-classical monocyte | 3 studies | 22% ± 5% | |
abnormal cell | 3 studies | 19% ± 2% | |
retinal cone cell | 3 studies | 39% ± 9% | |
ciliated cell | 3 studies | 31% ± 5% | |
GABAergic neuron | 3 studies | 31% ± 4% | |
glutamatergic neuron | 3 studies | 38% ± 7% | |
dendritic cell | 3 studies | 31% ± 10% | |
goblet cell | 3 studies | 21% ± 4% | |
intestinal crypt stem cell | 3 studies | 28% ± 6% | |
transit amplifying cell | 3 studies | 20% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
bladder | 100% | 3923.00 | 21 / 21 | 100% | 58.96 | 504 / 504 |
esophagus | 100% | 4507.43 | 1445 / 1445 | 100% | 48.62 | 183 / 183 |
intestine | 100% | 5485.32 | 966 / 966 | 100% | 83.46 | 527 / 527 |
liver | 100% | 3441.23 | 226 / 226 | 100% | 49.82 | 406 / 406 |
pancreas | 100% | 3003.46 | 328 / 328 | 100% | 36.84 | 178 / 178 |
stomach | 100% | 5643.09 | 359 / 359 | 100% | 75.94 | 286 / 286 |
uterus | 100% | 3656.65 | 170 / 170 | 100% | 66.47 | 459 / 459 |
kidney | 100% | 6848.49 | 89 / 89 | 100% | 69.12 | 900 / 901 |
thymus | 100% | 4382.21 | 653 / 653 | 100% | 58.89 | 604 / 605 |
prostate | 100% | 3134.58 | 245 / 245 | 100% | 37.72 | 501 / 502 |
skin | 100% | 3660.33 | 1809 / 1809 | 100% | 55.87 | 471 / 472 |
breast | 100% | 4116.02 | 459 / 459 | 100% | 47.33 | 1115 / 1118 |
adrenal gland | 100% | 4182.79 | 258 / 258 | 100% | 37.96 | 229 / 230 |
ovary | 100% | 3161.54 | 180 / 180 | 100% | 47.83 | 428 / 430 |
lung | 99% | 3199.51 | 574 / 578 | 100% | 43.51 | 1152 / 1155 |
brain | 99% | 3561.65 | 2615 / 2642 | 100% | 48.49 | 705 / 705 |
adipose | 100% | 4301.28 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 63.79 | 29 / 29 |
muscle | 100% | 11785.33 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 3027.54 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 63.53 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 17.13 | 1 / 1 |
blood vessel | 100% | 3155.82 | 1332 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 99% | 47.37 | 79 / 80 |
heart | 98% | 14750.08 | 847 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 65% | 2024.34 | 607 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006086 | Biological process | acetyl-CoA biosynthetic process from pyruvate |
GO_0006006 | Biological process | glucose metabolic process |
GO_0006099 | Biological process | tricarboxylic acid cycle |
GO_0005730 | Cellular component | nucleolus |
GO_0045254 | Cellular component | pyruvate dehydrogenase complex |
GO_0005759 | Cellular component | mitochondrial matrix |
GO_0005739 | Cellular component | mitochondrion |
GO_0005634 | Cellular component | nucleus |
GO_0034604 | Molecular function | pyruvate dehydrogenase (NAD+) activity |
GO_0005515 | Molecular function | protein binding |
GO_0004739 | Molecular function | pyruvate dehydrogenase (acetyl-transferring) activity |
Gene name | PDHA1 |
Protein name | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (EC 1.2.4.1) (PDHE1-A type I) Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial PDHA1 (EC 1.2.4.1) Pyruvate dehydrogenase E1 subunit alpha 1 Pyruvate dehydrogenase E1 component subunit alpha (EC 1.2.4.1) Pyruvate dehydrogenase E1-alpha-subunit Pyruvate dehydrogenase alpha subunit |
Synonyms | PHE1A |
Description | FUNCTION: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. . FUNCTION: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. . |
Accessions | ENST00000422285.7 [P08559-1] Q6LCA3 ENST00000696704.1 ENST00000423505.6 [P08559-4] ENST00000540249.5 [P08559-3] ENST00000355808.10 [P08559-2] Q5JPU2 A5YPB6 A0A8Q3WLK5 Q99724 P78557 Q5JPU1 Q5JPT9 Q99725 A0A8Q3WLI8 ENST00000423505.5 ENST00000417819.6 ENST00000379805.4 Q5JPU0 ENST00000696705.1 P08559 Q9UNV7 ENST00000355808.9 |