Name | Number of supported studies | Average coverage | |
---|---|---|---|
glutamatergic neuron | 11 studies | 64% ± 20% | |
GABAergic neuron | 9 studies | 47% ± 19% | |
neuron | 7 studies | 28% ± 12% | |
retina horizontal cell | 6 studies | 32% ± 11% | |
Mueller cell | 6 studies | 52% ± 18% | |
interneuron | 5 studies | 51% ± 27% | |
oligodendrocyte precursor cell | 5 studies | 24% ± 7% | |
retinal ganglion cell | 5 studies | 40% ± 5% | |
pancreatic A cell | 4 studies | 80% ± 14% | |
type B pancreatic cell | 4 studies | 34% ± 12% | |
glial cell | 4 studies | 23% ± 2% | |
granule cell | 4 studies | 43% ± 20% | |
pancreatic D cell | 3 studies | 59% ± 20% | |
GABAergic interneuron | 3 studies | 34% ± 10% | |
melanocyte | 3 studies | 51% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
thymus | 97% | 10125.23 | 631 / 653 | 80% | 197.00 | 481 / 605 |
brain | 90% | 2428.32 | 2385 / 2642 | 65% | 16.88 | 458 / 705 |
pancreas | 79% | 641.80 | 259 / 328 | 58% | 43.71 | 104 / 178 |
ovary | 94% | 1288.64 | 170 / 180 | 12% | 2.22 | 52 / 430 |
skin | 69% | 687.56 | 1248 / 1809 | 32% | 12.85 | 150 / 472 |
adrenal gland | 29% | 759.12 | 76 / 258 | 65% | 193.91 | 149 / 230 |
intestine | 63% | 728.25 | 612 / 966 | 2% | 1.17 | 11 / 527 |
esophagus | 59% | 816.67 | 858 / 1445 | 2% | 0.51 | 4 / 183 |
bladder | 48% | 516.90 | 10 / 21 | 3% | 3.39 | 14 / 504 |
lung | 35% | 425.53 | 200 / 578 | 11% | 18.00 | 130 / 1155 |
heart | 37% | 297.04 | 316 / 861 | 0% | 0 | 0 / 0 |
prostate | 29% | 182.60 | 70 / 245 | 0% | 0.09 | 2 / 502 |
stomach | 27% | 222.31 | 96 / 359 | 1% | 0.54 | 4 / 286 |
uterus | 8% | 35.62 | 13 / 170 | 5% | 0.95 | 23 / 459 |
blood vessel | 11% | 63.36 | 151 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 11% | 1.34 | 9 / 80 |
breast | 7% | 36.23 | 34 / 459 | 4% | 1.33 | 41 / 1118 |
adipose | 8% | 38.60 | 97 / 1204 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 7% | 0.78 | 3 / 45 |
liver | 0% | 0 | 0 / 226 | 0% | 0.04 | 1 / 406 |
kidney | 0% | 0 | 0 / 89 | 0% | 0.02 | 2 / 901 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0016486 | Biological process | peptide hormone processing |
GO_0016540 | Biological process | protein autoprocessing |
GO_0007399 | Biological process | nervous system development |
GO_0034230 | Biological process | enkephalin processing |
GO_0030070 | Biological process | insulin processing |
GO_0006508 | Biological process | proteolysis |
GO_0034231 | Biological process | islet amyloid polypeptide processing |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0043204 | Cellular component | perikaryon |
GO_0005615 | Cellular component | extracellular space |
GO_0030141 | Cellular component | secretory granule |
GO_0005654 | Cellular component | nucleoplasm |
GO_0030425 | Cellular component | dendrite |
GO_0043005 | Cellular component | neuron projection |
GO_0016020 | Cellular component | membrane |
GO_0030133 | Cellular component | transport vesicle |
GO_0005515 | Molecular function | protein binding |
GO_0004252 | Molecular function | serine-type endopeptidase activity |
Gene name | PCSK2 |
Protein name | Neuroendocrine convertase 2 (NEC 2) (EC 3.4.21.94) (KEX2-like endoprotease 2) (Prohormone convertase 2) (Proprotein convertase 2) (PC2) |
Synonyms | NEC2 |
Description | FUNCTION: Serine endopeptidase which is involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Responsible for the release of glucagon from proglucagon in pancreatic A cells. . |
Accessions | ENST00000377899.5 [P16519-3] ENST00000536609.1 [P16519-2] ENST00000262545.7 [P16519-1] P16519 |