PCMTD2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0036211Biological processprotein modification process
GO_0005737Cellular componentcytoplasm
GO_0004719Molecular functionprotein-L-isoaspartate (D-aspartate) O-methyltransferase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene namePCMTD2
Protein nameProtein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 (Protein-L-isoaspartate O-methyltransferase domain-containing protein 2)
PCMTD2 protein
Protein-L-isoaspartate O-methyltransferase domain-containing protein 2
Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
SynonymsC20orf36
DescriptionFUNCTION: May act as a substrate recognition component of an ECS (Elongin BC-CUL5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. May bind to the methyltransferase cofactor S-adenosylmethionine (AdoMet) via the N-terminal AdoMet binding motif, but probably does not display methyltransferase activity. .

AccessionsENST00000610196.1
V9GZ41
ENST00000628846.1
I6L9C7
ENST00000631244.2 [Q9NV79-2]
ENST00000609372.1
ENST00000610074.1
ENST00000629502.1
ENST00000308824.11 [Q9NV79-1]
Q6PIM4
V9GYG6
ENST00000629544.1
ENST00000615818.3 [Q9NV79-1]
F8W9F3
Q9NV79
ENST00000609764.1
ENST00000369758.8 [Q9NV79-2]
V9GYL1
A0A0G2JR02
ENST00000618274.4
ENST00000628717.1
A0A0G2JM70
V9GYZ4
ENST00000609818.1
V9GYZ7
ENST00000299468.12
ENST00000627852.1
ENST00000608844.1
ENST00000627415.2 [Q9NV79-1]