Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| plasmacytoid dendritic cell | 14 studies | 33% ± 10% | |
| glutamatergic neuron | 8 studies | 42% ± 23% | |
| retinal cone cell | 6 studies | 30% ± 9% | |
| GABAergic neuron | 6 studies | 39% ± 18% | |
| retinal rod cell | 5 studies | 22% ± 5% | |
| amacrine cell | 4 studies | 21% ± 5% | |
| retinal ganglion cell | 4 studies | 46% ± 25% | |
| neuron | 3 studies | 23% ± 6% | |
| retinal bipolar neuron | 3 studies | 19% ± 2% | |
| interneuron | 3 studies | 48% ± 20% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 94% | 24317.05 | 2490 / 2642 | 81% | 48.72 | 571 / 705 |
| ureter | 0% | 0 | 0 / 0 | 100% | 3.65 | 1 / 1 |
| ovary | 0% | 0 | 0 / 180 | 85% | 8.49 | 367 / 430 |
| prostate | 0% | 0 | 0 / 245 | 70% | 3.02 | 353 / 502 |
| lymph node | 0% | 0 | 0 / 0 | 69% | 5.65 | 20 / 29 |
| breast | 0% | 0 | 0 / 459 | 61% | 3.32 | 687 / 1118 |
| uterus | 0% | 0 | 0 / 170 | 32% | 3.01 | 147 / 459 |
| bladder | 0% | 0 | 0 / 21 | 30% | 1.91 | 150 / 504 |
| adrenal gland | 0% | 15.43 | 1 / 258 | 28% | 1.92 | 64 / 230 |
| pancreas | 0% | 5.86 | 1 / 328 | 22% | 1.26 | 40 / 178 |
| lung | 0% | 0 | 0 / 578 | 22% | 1.17 | 259 / 1155 |
| tonsil | 0% | 0 | 0 / 0 | 20% | 1.18 | 9 / 45 |
| thymus | 0% | 0 | 0 / 653 | 20% | 0.81 | 120 / 605 |
| liver | 0% | 0 | 0 / 226 | 20% | 1.32 | 80 / 406 |
| eye | 0% | 0 | 0 / 0 | 19% | 2.95 | 15 / 80 |
| kidney | 0% | 0 | 0 / 89 | 18% | 0.97 | 162 / 901 |
| esophagus | 0% | 2.95 | 2 / 1445 | 12% | 0.63 | 22 / 183 |
| skin | 0% | 0.90 | 1 / 1809 | 10% | 0.41 | 47 / 472 |
| stomach | 0% | 0 | 0 / 359 | 9% | 0.60 | 25 / 286 |
| heart | 8% | 153.84 | 69 / 861 | 0% | 0 | 0 / 0 |
| intestine | 0% | 4.82 | 3 / 966 | 6% | 0.26 | 31 / 527 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| adipose | 0% | 0 | 0 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 0 | 0 / 1335 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| GO_0072659 | Biological process | protein localization to plasma membrane |
| GO_0048488 | Biological process | synaptic vesicle endocytosis |
| GO_0045806 | Biological process | negative regulation of endocytosis |
| GO_0007010 | Biological process | cytoskeleton organization |
| GO_0097320 | Biological process | plasma membrane tubulation |
| GO_0048812 | Biological process | neuron projection morphogenesis |
| GO_1900006 | Biological process | positive regulation of dendrite development |
| GO_0007015 | Biological process | actin filament organization |
| GO_0030100 | Biological process | regulation of endocytosis |
| GO_0072657 | Biological process | protein localization to membrane |
| GO_0032587 | Cellular component | ruffle membrane |
| GO_0098833 | Cellular component | presynaptic endocytic zone |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0030137 | Cellular component | COPI-coated vesicle |
| GO_0048471 | Cellular component | perinuclear region of cytoplasm |
| GO_0043679 | Cellular component | axon terminus |
| GO_0098684 | Cellular component | photoreceptor ribbon synapse |
| GO_0005829 | Cellular component | cytosol |
| GO_0045202 | Cellular component | synapse |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005768 | Cellular component | endosome |
| GO_0030659 | Cellular component | cytoplasmic vesicle membrane |
| GO_0005543 | Molecular function | phospholipid binding |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0008092 | Molecular function | cytoskeletal protein binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | PACSIN1 |
| Protein name | Protein kinase C and casein kinase substrate in neurons protein 1 PACSIN1 protein Protein kinase C and casein kinase substrate in neurons 1 Protein kinase C and casein kinase substrate in neurons protein 1 (Syndapin-1) |
| Synonyms | KIAA1379 hCG_16082 |
| Description | FUNCTION: Plays a role in the reorganization of the microtubule cytoskeleton via its interaction with MAPT; this decreases microtubule stability and inhibits MAPT-induced microtubule polymerization. Plays a role in cellular transport processes by recruiting DNM1, DNM2 and DNM3 to membranes. Plays a role in the reorganization of the actin cytoskeleton and in neuron morphogenesis via its interaction with COBL and WASL, and by recruiting COBL to the cell cortex. Plays a role in the regulation of neurite formation, neurite branching and the regulation of neurite length. Required for normal synaptic vesicle endocytosis; this process retrieves previously released neurotransmitters to accommodate multiple cycles of neurotransmission. Required for normal excitatory and inhibitory synaptic transmission (By similarity). Binds to membranes via its F-BAR domain and mediates membrane tubulation. . |
| Accessions | ENST00000244458.7 ENST00000620693.4 ENST00000538621.2 ENST00000374043.6 Q9BY11 Q5TZC3 A2VCM5 F6U236 |
