OTX1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of OTX1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of OTX1 at tissue level.

III. Associated gene sets

GO_0042472Biological processinner ear morphogenesis
GO_0022037Biological processmetencephalon development
GO_0009952Biological processanterior/posterior pattern specification
GO_0048852Biological processdiencephalon morphogenesis
GO_0030901Biological processmidbrain development
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene nameOTX1
Protein nameHomeobox protein OTX1
Homeobox protein OTX1 (Orthodenticle homolog 1)
Orthodenticle homeobox 1
Synonyms
DescriptionFUNCTION: Probably plays a role in the development of the brain and the sense organs. Can bind to the BCD target sequence (BTS): 5'-TCTAATCCC-3'.

AccessionsB5MC54
Q9P2R2
ENST00000282549.7
P32242
ENST00000405984.8
ENST00000366671.7