OLIG3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of OLIG3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of OLIG3 at tissue level.

III. Associated gene sets

GO_0021520Biological processspinal cord motor neuron cell fate specification
GO_0007423Biological processsensory organ development
GO_0061564Biological processaxon development
GO_0097476Biological processspinal cord motor neuron migration
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0070888Molecular functionE-box binding
GO_0046983Molecular functionprotein dimerization activity
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene nameOLIG3
Protein nameOligodendrocyte transcription factor 3 (Oligo3) (Class B basic helix-loop-helix protein 7) (bHLHb7) (Class E basic helix-loop-helix protein 20) (bHLHe20)
SynonymsBHLHE20
BHLHB7
DescriptionFUNCTION: May determine the distinct specification program of class A neurons in the dorsal part of the spinal cord and suppress specification of class B neurons.

AccessionsENST00000367734.4
Q7RTU3