OLFM2 | OmnibusX

Name	Number of supported studies	Average coverage
astrocyte	16 studies	39% ± 16%	Explore
oligodendrocyte precursor cell	14 studies	45% ± 17%	Explore
GABAergic neuron	8 studies	35% ± 19%	Explore
neuron	6 studies	35% ± 14%	Explore
interneuron	6 studies	34% ± 20%	Explore
glutamatergic neuron	5 studies	42% ± 15%	Explore
pericyte	5 studies	23% ± 7%	Explore
Mueller cell	5 studies	26% ± 7%	Explore
GABAergic interneuron	3 studies	22% ± 5%	Explore
adipocyte	3 studies	24% ± 5%	Explore

Name	Number of supported studies	Average coverage
brain	12 studies	24% ± 11%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	7675.45	2630 / 2642	100%	356.67	702 / 705
liver	64%	1685.10	145 / 226	89%	87.04	361 / 406
prostate	55%	700.22	135 / 245	95%	49.88	475 / 502
adrenal gland	99%	2570.86	255 / 258	50%	63.65	114 / 230
breast	79%	2118.54	361 / 459	68%	30.93	757 / 1118
thymus	81%	1164.68	529 / 653	46%	17.51	277 / 605
uterus	72%	1320.86	122 / 170	49%	30.36	225 / 459
skin	80%	4123.78	1440 / 1809	39%	22.42	183 / 472
ovary	51%	645.78	92 / 180	61%	34.01	262 / 430
lung	45%	649.35	261 / 578	59%	25.68	683 / 1155
adipose	87%	2399.34	1053 / 1204	0%	0	0 / 0
pancreas	5%	56.72	18 / 328	53%	17.23	94 / 178
esophagus	7%	63.19	94 / 1445	50%	28.54	92 / 183
eye	0%	0	0 / 0	53%	15.33	42 / 80
tonsil	0%	0	0 / 0	42%	15.92	19 / 45
bladder	5%	35.24	1 / 21	31%	11.86	155 / 504
kidney	9%	119.62	8 / 89	22%	8.82	199 / 901
stomach	1%	9.72	4 / 359	26%	10.87	75 / 286
intestine	7%	72.53	69 / 966	18%	5.37	97 / 527
heart	16%	189.18	135 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	7%	1.21	2 / 29
blood vessel	6%	97.31	86 / 1335	0%	0	0 / 0
muscle	0%	2.08	2 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007165	Biological process	signal transduction
GO_1905174	Biological process	regulation of vascular associated smooth muscle cell dedifferentiation
GO_0051152	Biological process	positive regulation of smooth muscle cell differentiation
GO_0009306	Biological process	protein secretion
GO_0005615	Cellular component	extracellular space
GO_0005654	Cellular component	nucleoplasm
GO_0045202	Cellular component	synapse
GO_0005576	Cellular component	extracellular region
GO_0032281	Cellular component	AMPA glutamate receptor complex
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0005515	Molecular function	protein binding

Gene name	OLFM2
Protein name	Alternative protein OLFM2 Olfactomedin 2 Noelin-2 (Olfactomedin-2)
Synonyms	NOE2
Description	FUNCTION: Involved in transforming growth factor beta (TGF-beta)-induced smooth muscle differentiation. TGF-beta induces expression and translocation of OLFM2 to the nucleus where it binds to SRF, causing its dissociation from the transcriptional repressor HEY2/HERP1 and facilitating binding of SRF to target genes . Plays a role in AMPAR complex organization (By similarity). Is a regulator of vascular smooth-muscle cell (SMC) phenotypic switching, that acts by promoting RUNX2 and inhibiting MYOCD binding to SRF. SMC phenotypic switching is the process through which vascular SMCs undergo transition between a quiescent contractile phenotype and a proliferative synthetic phenotype in response to pathological stimuli. SMC phenotypic plasticity is essential for vascular development and remodeling (By similarity). .
Accessions	O95897 L8E9J3 ENST00000264833.9 ENST00000590841.5 K7EIS8 K7EKW2 ENST00000593091.2 ENST00000592448.1 K7ELC6

OLFM2 report