ODAM report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ODAM at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ODAM at tissue level.

III. Associated gene sets

GO_0042475Biological processodontogenesis of dentin-containing tooth
GO_0010628Biological processpositive regulation of gene expression
GO_0060054Biological processpositive regulation of epithelial cell proliferation involved in wound healing
GO_0006954Biological processinflammatory response
GO_0001934Biological processpositive regulation of protein phosphorylation
GO_0031214Biological processbiomineral tissue development
GO_0043547Biological processpositive regulation of GTPase activity
GO_0032956Biological processregulation of actin cytoskeleton organization
GO_0099512Cellular componentsupramolecular fiber
GO_0005615Cellular componentextracellular space
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005576Cellular componentextracellular region
GO_0071944Cellular componentcell periphery
GO_0072686Cellular componentmitotic spindle
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameODAM
Protein nameOdontogenic, ameloblast associated
Odontogenic ameloblast-associated protein (Apin)
SynonymsAPIN
DescriptionFUNCTION: Tooth-associated epithelia protein that probably plays a role in odontogenesis, the complex process that results in the initiation and generation of the tooth. May be incorporated in the enamel matrix at the end of mineralization process. Involved in the induction of RHOA activity via interaction with ARHGEF and expression of downstream factors such as ROCK. Plays a role in attachment of the junctional epithelium to the tooth surface. .

FUNCTION: Tooth-associated epithelia protein that probably plays a role in odontogenesis, the complex process that results in the initiation and generation of the tooth. May be incorporated in the enamel matrix at the end of mineralization process. Involved in the induction of RHOA activity via interaction with ARHGEF and expression of downstream factors such as ROCK. Plays a role in attachment of the junctional epithelium to the tooth surface. .

FUNCTION: Tooth-associated epithelia protein that probably plays a role in odontogenesis, the complex process that results in the initiation and generation of the tooth. May be incorporated in the enamel matrix at the end of mineralization process. Involved in the induction of RHOA activity via interaction with ARHGEF and expression of downstream factors such as ROCK. Plays a role in attachment of the junctional epithelium to the tooth surface. .

AccessionsENST00000514097.5
ENST00000683306.1
H0YA46
H0Y8T7
A1E959
ENST00000510709.6
ENST00000510847.1
D6RA81
ENST00000396094.6