Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 15 studies | 24% ± 10% | |
fibroblast | 9 studies | 23% ± 8% | |
astrocyte | 8 studies | 30% ± 12% | |
microglial cell | 7 studies | 22% ± 6% | |
adipocyte | 7 studies | 22% ± 4% | |
GABAergic neuron | 7 studies | 35% ± 19% | |
oligodendrocyte | 7 studies | 25% ± 7% | |
interneuron | 6 studies | 33% ± 21% | |
macrophage | 6 studies | 26% ± 5% | |
epithelial cell | 6 studies | 34% ± 18% | |
glutamatergic neuron | 6 studies | 44% ± 24% | |
ciliated cell | 5 studies | 30% ± 13% | |
myeloid cell | 5 studies | 18% ± 2% | |
endothelial cell of lymphatic vessel | 5 studies | 27% ± 9% | |
pericyte | 5 studies | 24% ± 8% | |
smooth muscle cell | 5 studies | 19% ± 2% | |
lymphocyte | 4 studies | 26% ± 6% | |
oligodendrocyte precursor cell | 4 studies | 29% ± 9% | |
type I pneumocyte | 4 studies | 21% ± 6% | |
neuron | 3 studies | 29% ± 10% | |
T cell | 3 studies | 25% ± 6% | |
basal cell | 3 studies | 31% ± 19% | |
hepatocyte | 3 studies | 37% ± 25% | |
ependymal cell | 3 studies | 40% ± 11% | |
monocyte | 3 studies | 19% ± 2% | |
natural killer cell | 3 studies | 19% ± 2% | |
transit amplifying cell | 3 studies | 39% ± 27% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 3343.55 | 1445 / 1445 | 100% | 61.15 | 183 / 183 |
lung | 100% | 3870.10 | 578 / 578 | 100% | 42.77 | 1154 / 1155 |
ovary | 100% | 3887.81 | 180 / 180 | 100% | 43.47 | 429 / 430 |
stomach | 100% | 2508.74 | 359 / 359 | 100% | 38.81 | 285 / 286 |
intestine | 100% | 3362.84 | 966 / 966 | 99% | 34.72 | 523 / 527 |
breast | 100% | 4212.57 | 459 / 459 | 99% | 49.46 | 1106 / 1118 |
bladder | 100% | 3575.10 | 21 / 21 | 98% | 34.81 | 496 / 504 |
uterus | 100% | 4177.22 | 170 / 170 | 98% | 39.00 | 451 / 459 |
skin | 100% | 4549.23 | 1809 / 1809 | 97% | 48.22 | 460 / 472 |
thymus | 100% | 3390.51 | 653 / 653 | 96% | 22.27 | 581 / 605 |
prostate | 100% | 2713.53 | 245 / 245 | 96% | 26.12 | 482 / 502 |
pancreas | 99% | 1646.09 | 324 / 328 | 97% | 23.90 | 173 / 178 |
brain | 96% | 1883.19 | 2547 / 2642 | 99% | 30.25 | 701 / 705 |
kidney | 100% | 2050.02 | 89 / 89 | 93% | 26.07 | 840 / 901 |
adrenal gland | 100% | 2652.44 | 258 / 258 | 87% | 17.87 | 200 / 230 |
liver | 100% | 1824.46 | 226 / 226 | 86% | 19.42 | 350 / 406 |
adipose | 100% | 4426.22 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 3518.31 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 41.78 | 29 / 29 |
muscle | 100% | 3853.12 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 3665.61 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 14.97 | 1 / 1 |
tonsil | 0% | 0 | 0 / 0 | 98% | 48.84 | 44 / 45 |
heart | 95% | 1937.02 | 820 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 95% | 3960.78 | 883 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 90% | 21.56 | 72 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0046832 | Biological process | negative regulation of RNA export from nucleus |
GO_0006405 | Biological process | RNA export from nucleus |
GO_0051028 | Biological process | mRNA transport |
GO_0051292 | Biological process | nuclear pore complex assembly |
GO_1990000 | Biological process | amyloid fibril formation |
GO_0046718 | Biological process | symbiont entry into host cell |
GO_0006606 | Biological process | protein import into nucleus |
GO_0006913 | Biological process | nucleocytoplasmic transport |
GO_0075732 | Biological process | viral penetration into host nucleus |
GO_0042405 | Cellular component | nuclear inclusion body |
GO_0005730 | Cellular component | nucleolus |
GO_0005643 | Cellular component | nuclear pore |
GO_0016020 | Cellular component | membrane |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005635 | Cellular component | nuclear envelope |
GO_0044615 | Cellular component | nuclear pore nuclear basket |
GO_0005829 | Cellular component | cytosol |
GO_0043657 | Cellular component | host cell |
GO_0031965 | Cellular component | nuclear membrane |
GO_0034399 | Cellular component | nuclear periphery |
GO_0003677 | Molecular function | DNA binding |
GO_0043495 | Molecular function | protein-membrane adaptor activity |
GO_0008139 | Molecular function | nuclear localization sequence binding |
GO_0017056 | Molecular function | structural constituent of nuclear pore |
GO_0042802 | Molecular function | identical protein binding |
GO_0140693 | Molecular function | molecular condensate scaffold activity |
GO_0046872 | Molecular function | metal ion binding |
GO_0005515 | Molecular function | protein binding |
Gene name | NUP153 |
Protein name | Nuclear pore complex protein Nup153 (153 kDa nucleoporin) (Nucleoporin Nup153) |
Synonyms | |
Description | FUNCTION: Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC essential for normal nucleocytoplasmic transport of proteins and mRNAs. Involved in the quality control and retention of unspliced mRNAs in the nucleus; in association with TPR, regulates the nuclear export of unspliced mRNA species bearing constitutive transport element (CTE) in a NXF1- and KHDRBS1-independent manner. Mediates TPR anchoring to the nuclear membrane at NPC. The repeat-containing domain may be involved in anchoring other components of the NPC to the pore membrane. Possible DNA-binding subunit of the nuclear pore complex (NPC). .; FUNCTION: (Microbial infection) Interacts with HIV-1 caspid protein P24 and thereby promotes the integration of the virus in the nucleus of non-dividing cells (in vitro). .; FUNCTION: (Microbial infection) Binds HIV-2 protein vpx and thereby promotes the nuclear translocation of the lentiviral genome (in vitro). . |
Accessions | ENST00000537253.5 [P49790-3] P49790 ENST00000613258.4 [P49790-2] ENST00000262077.3 [P49790-1] |