NUDT14 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006753Biological processnucleoside phosphate metabolic process
GO_0019693Biological processribose phosphate metabolic process
GO_0018279Biological processprotein N-linked glycosylation via asparagine
GO_0005829Cellular componentcytosol
GO_0047631Molecular functionADP-ribose diphosphatase activity
GO_0008768Molecular functionUDP-sugar diphosphatase activity
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameNUDT14
Protein nameNudix (Nucleoside diphosphate linked moiety X)-type motif 14, isoform CRA_a (cDNA FLJ46324 fis, clone TESTI4043223, highly similar to Uridine diphosphate glucose pyrophosphatase (EC 3.6.1.45))
Uridine diphosphate glucose pyrophosphatase NUDT14 (UDPG pyrophosphatase) (UGPPase) (EC 3.6.1.45) (Nucleoside diphosphate-linked moiety X motif 14) (Nudix motif 14)
Nudix hydrolase 14
SynonymsUGPP
hCG_19132
DescriptionFUNCTION: Hydrolyzes UDP-glucose to glucose 1-phosphate and UMP and ADP-ribose to ribose 5-phosphate and AMP. The physiological substrate is probably UDP-glucose. Poor activity on other substrates such as ADP-glucose, CDP-glucose, GDP-glucose and GDP-mannose.

AccessionsF8VU44
ENST00000546553.1
ENST00000392568.7
B3KXY7
O95848