NME7 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006183Biological processGTP biosynthetic process
GO_0010968Biological processregulation of microtubule nucleation
GO_0006228Biological processUTP biosynthetic process
GO_0006241Biological processCTP biosynthetic process
GO_0005879Cellular componentaxonemal microtubule
GO_0005813Cellular componentcentrosome
GO_0000931Cellular componentgamma-tubulin ring complex
GO_0031514Cellular componentmotile cilium
GO_0005737Cellular componentcytoplasm
GO_0005829Cellular componentcytosol
GO_0005819Cellular componentspindle
GO_0005634Cellular componentnucleus
GO_0004550Molecular functionnucleoside diphosphate kinase activity
GO_0005515Molecular functionprotein binding
GO_0005524Molecular functionATP binding
GO_0008408Molecular function3'-5' exonuclease activity
GO_0004672Molecular functionprotein kinase activity

IV. Literature review

[source]
Gene nameNME7
Protein nameNME/NM23 family member 7
Nucleoside diphosphate kinase homolog 7 (NDK 7) (NDP kinase homolog 7) (3'-5' exonuclease NME7) (EC 3.1.-.-) (Protein kinase NME7) (EC 2.7.-.-) (nm23-H7)
Nucleoside diphosphate kinase 7 (EC 2.7.4.6)
Synonyms
DescriptionFUNCTION: Possesses an intrinsic kinase activity . Displays 3'-5' exonuclease activity with a preference for single-stranded DNA . Does not seem to have nucleoside diphosphate kinase activity . Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating . Functional component of the gamma-tubulin ring complex, implicated in the regulation of the microtubule-nucleating activity of the gamma-tubulin ring complex in centrosomes, in a kinase activity-dependent manner . .

AccessionsENST00000472647.5 [Q9Y5B8-2]
Q9Y5B8
ENST00000525440.5
ENST00000528517.5
ENST00000367811.8 [Q9Y5B8-1]
E9PNU1
B4DXC8