I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| fibroblast | 11 studies | 23% ± 9% | |
| pericyte | 7 studies | 27% ± 13% | |
| endothelial cell | 5 studies | 23% ± 4% | |
| connective tissue cell | 3 studies | 26% ± 13% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| fibroblast | 11 studies | 23% ± 9% | |
| pericyte | 7 studies | 27% ± 13% | |
| endothelial cell | 5 studies | 23% ± 4% | |
| connective tissue cell | 3 studies | 26% ± 13% |
Insufficient scRNA-seq data for expression of NID2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 99% | 1616.89 | 456 / 459 | 89% | 19.24 | 997 / 1118 |
| thymus | 100% | 3776.43 | 653 / 653 | 87% | 46.48 | 529 / 605 |
| intestine | 86% | 1085.81 | 827 / 966 | 79% | 11.24 | 415 / 527 |
| esophagus | 81% | 1347.66 | 1174 / 1445 | 82% | 15.14 | 150 / 183 |
| lung | 97% | 995.33 | 559 / 578 | 65% | 7.73 | 749 / 1155 |
| ovary | 100% | 3043.06 | 180 / 180 | 60% | 8.16 | 257 / 430 |
| bladder | 100% | 1205.14 | 21 / 21 | 55% | 7.50 | 276 / 504 |
| kidney | 80% | 618.46 | 71 / 89 | 66% | 15.16 | 598 / 901 |
| stomach | 56% | 1014.95 | 202 / 359 | 86% | 15.22 | 247 / 286 |
| uterus | 99% | 1261.21 | 168 / 170 | 38% | 6.93 | 173 / 459 |
| adrenal gland | 84% | 813.35 | 218 / 258 | 50% | 5.74 | 114 / 230 |
| prostate | 93% | 1088.59 | 228 / 245 | 34% | 2.39 | 172 / 502 |
| pancreas | 45% | 256.82 | 148 / 328 | 80% | 11.39 | 143 / 178 |
| skin | 51% | 3374.46 | 926 / 1809 | 56% | 7.03 | 262 / 472 |
| adipose | 100% | 2206.45 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| heart | 97% | 1318.11 | 832 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 87% | 799.87 | 1161 / 1335 | 0% | 0 | 0 / 0 |
| liver | 23% | 116.23 | 52 / 226 | 22% | 1.64 | 88 / 406 |
| tonsil | 0% | 0 | 0 / 0 | 42% | 5.56 | 19 / 45 |
| brain | 2% | 9.14 | 52 / 2642 | 39% | 4.94 | 272 / 705 |
| muscle | 33% | 175.98 | 268 / 803 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 24% | 2.29 | 7 / 29 |
| spleen | 9% | 43.00 | 21 / 241 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 3% | 0.12 | 2 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0071711 | Biological process | basement membrane organization |
| GO_0007155 | Biological process | cell adhesion |
| GO_0007160 | Biological process | cell-matrix adhesion |
| GO_0005604 | Cellular component | basement membrane |
| GO_0005615 | Cellular component | extracellular space |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005576 | Cellular component | extracellular region |
| GO_0062023 | Cellular component | collagen-containing extracellular matrix |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005201 | Molecular function | extracellular matrix structural constituent |
| GO_0005509 | Molecular function | calcium ion binding |
| GO_0005518 | Molecular function | collagen binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | NID2 |
| Protein name | NID2 protein Nidogen 2 Alternative protein NID2 Nidogen-2 (NID-2) (Osteonidogen) |
| Synonyms | |
| Description | FUNCTION: Cell adhesion glycoprotein which is widely distributed in basement membranes. Binds to collagens I and IV, to perlecan and to laminin 1. Does not bind fibulins. It probably has a role in cell-extracellular matrix interactions. |
| Accessions | Q14112 H0YJV3 L8EAL3 Q8IV28 ENST00000216286.10 [Q14112-1] ENST00000556572.1 |
