Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 19 studies | 40% ± 20% | |
ciliated cell | 15 studies | 34% ± 11% | |
endothelial cell | 15 studies | 30% ± 14% | |
oligodendrocyte | 13 studies | 36% ± 15% | |
oligodendrocyte precursor cell | 11 studies | 37% ± 15% | |
fibroblast | 11 studies | 25% ± 9% | |
GABAergic neuron | 10 studies | 47% ± 24% | |
glutamatergic neuron | 9 studies | 50% ± 24% | |
microglial cell | 9 studies | 32% ± 13% | |
adipocyte | 8 studies | 27% ± 7% | |
neuron | 6 studies | 40% ± 13% | |
epithelial cell | 6 studies | 29% ± 12% | |
interneuron | 6 studies | 55% ± 25% | |
macrophage | 6 studies | 27% ± 9% | |
retinal cone cell | 6 studies | 26% ± 11% | |
cardiac muscle cell | 5 studies | 27% ± 6% | |
Mueller cell | 5 studies | 30% ± 16% | |
pericyte | 5 studies | 23% ± 7% | |
granule cell | 4 studies | 26% ± 5% | |
retinal ganglion cell | 4 studies | 39% ± 25% | |
amacrine cell | 4 studies | 30% ± 11% | |
connective tissue cell | 4 studies | 18% ± 2% | |
endothelial cell of lymphatic vessel | 4 studies | 22% ± 2% | |
smooth muscle cell | 4 studies | 24% ± 3% | |
GABAergic interneuron | 3 studies | 42% ± 4% | |
glial cell | 3 studies | 24% ± 7% | |
GABAergic amacrine cell | 3 studies | 30% ± 10% | |
glycinergic amacrine cell | 3 studies | 25% ± 2% | |
retinal rod cell | 3 studies | 22% ± 4% | |
ependymal cell | 3 studies | 57% ± 11% | |
type I pneumocyte | 3 studies | 20% ± 2% | |
lymphocyte | 3 studies | 21% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 1635.91 | 2642 / 2642 | 100% | 16.66 | 705 / 705 |
prostate | 100% | 1075.69 | 245 / 245 | 99% | 12.82 | 499 / 502 |
breast | 100% | 1130.93 | 459 / 459 | 98% | 9.46 | 1094 / 1118 |
esophagus | 100% | 1036.39 | 1444 / 1445 | 98% | 6.68 | 179 / 183 |
thymus | 100% | 1241.49 | 653 / 653 | 98% | 7.84 | 591 / 605 |
kidney | 99% | 764.09 | 88 / 89 | 97% | 7.63 | 876 / 901 |
adrenal gland | 99% | 1137.70 | 256 / 258 | 95% | 10.14 | 219 / 230 |
lung | 100% | 956.37 | 577 / 578 | 95% | 5.57 | 1092 / 1155 |
uterus | 100% | 1431.40 | 170 / 170 | 91% | 5.47 | 416 / 459 |
skin | 98% | 1008.67 | 1772 / 1809 | 92% | 8.50 | 432 / 472 |
stomach | 100% | 974.89 | 359 / 359 | 87% | 4.03 | 249 / 286 |
pancreas | 91% | 401.33 | 298 / 328 | 96% | 6.26 | 171 / 178 |
bladder | 100% | 1357.76 | 21 / 21 | 86% | 4.27 | 431 / 504 |
intestine | 100% | 1131.62 | 964 / 966 | 81% | 3.63 | 428 / 527 |
ovary | 100% | 1651.99 | 180 / 180 | 69% | 2.49 | 295 / 430 |
liver | 89% | 347.10 | 202 / 226 | 53% | 1.90 | 216 / 406 |
blood vessel | 100% | 1402.01 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 751.47 | 241 / 241 | 0% | 0 | 0 / 0 |
adipose | 100% | 1117.94 | 1203 / 1204 | 0% | 0 | 0 / 0 |
muscle | 98% | 653.36 | 790 / 803 | 0% | 0 | 0 / 0 |
heart | 95% | 911.64 | 820 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 87% | 4.81 | 39 / 45 |
lymph node | 0% | 0 | 0 / 0 | 79% | 4.14 | 23 / 29 |
eye | 0% | 0 | 0 / 0 | 64% | 3.64 | 51 / 80 |
peripheral blood | 26% | 324.08 | 242 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0060271 | Biological process | cilium assembly |
GO_0051301 | Biological process | cell division |
GO_0006468 | Biological process | protein phosphorylation |
GO_0034451 | Cellular component | centriolar satellite |
GO_0005813 | Cellular component | centrosome |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0000242 | Cellular component | pericentriolar material |
GO_0005634 | Cellular component | nucleus |
GO_0106310 | Molecular function | protein serine kinase activity |
GO_0004713 | Molecular function | protein tyrosine kinase activity |
GO_0071889 | Molecular function | 14-3-3 protein binding |
GO_0004674 | Molecular function | protein serine/threonine kinase activity |
GO_0004672 | Molecular function | protein kinase activity |
GO_0046872 | Molecular function | metal ion binding |
GO_0005524 | Molecular function | ATP binding |
GO_0016301 | Molecular function | kinase activity |
GO_0005515 | Molecular function | protein binding |
Gene name | NEK1 |
Protein name | non-specific serine/threonine protein kinase (EC 2.7.11.1) NIMA related kinase 1 Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1) (Renal carcinoma antigen NY-REN-55) |
Synonyms | KIAA1901 |
Description | FUNCTION: Phosphorylates serines and threonines, but also appears to possess tyrosine kinase activity . Involved in DNA damage checkpoint control and for proper DNA damage repair . In response to injury that includes DNA damage, NEK1 phosphorylates VDAC1 to limit mitochondrial cell death . May be implicated in the control of meiosis (By similarity). Involved in cilium assembly . . |
Accessions | ENST00000507142.6 [Q96PY6-3] A0A8I5QJM8 ENST00000687219.1 ENST00000512193.5 [Q96PY6-4] ENST00000510533.5 [Q96PY6-2] ENST00000687528.1 ENST00000692868.1 ENST00000439128.6 [Q96PY6-1] D6RBG5 ENST00000686697.1 ENST00000505119.2 A0A8I5KT19 ENST00000685111.1 ENST00000688934.1 ENST00000693085.1 A0A8I5QL42 ENST00000510108.1 A0A8I5KUL6 ENST00000692450.1 ENST00000693604.1 ENST00000687643.1 ENST00000511633.5 [Q96PY6-6] A0A8I5KWD5 A0A8I5KQ77 A0A8I5KSI3 H0Y8M6 A0A8I5KRM5 Q96PY6 |