NAB2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of NAB2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of NAB2 at tissue level.

III. Associated gene sets

GO_0016480Biological processnegative regulation of transcription by RNA polymerase III
GO_0014037Biological processSchwann cell differentiation
GO_0001958Biological processendochondral ossification
GO_0042552Biological processmyelination
GO_0045682Biological processregulation of epidermis development
GO_0006355Biological processregulation of DNA-templated transcription
GO_0005654Cellular componentnucleoplasm
GO_0005634Cellular componentnucleus
GO_0008134Molecular functiontranscription factor binding
GO_0003714Molecular functiontranscription corepressor activity
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding
GO_0003712Molecular functiontranscription coregulator activity

IV. Literature review

[source]
Gene nameNAB2
Protein nameNGFI-A-binding protein 2 (EGR-1-binding protein 2) (Melanoma-associated delayed early response protein) (Protein MADER)
SynonymsMADER
DescriptionFUNCTION: Acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2. Isoform 2 lacks repression ability (By similarity). .

AccessionsQ15742
ENST00000342556.6 [Q15742-3]
ENST00000300131.8 [Q15742-1]