MYRIP report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0032024Biological processpositive regulation of insulin secretion
GO_0006886Biological processintracellular protein transport
GO_0042470Cellular componentmelanosome
GO_0001750Cellular componentphotoreceptor outer segment
GO_0045202Cellular componentsynapse
GO_0030864Cellular componentcortical actin cytoskeleton
GO_0031045Cellular componentdense core granule
GO_0000145Cellular componentexocyst
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0030133Cellular componenttransport vesicle
GO_0017022Molecular functionmyosin binding
GO_0051018Molecular functionprotein kinase A binding
GO_0005515Molecular functionprotein binding
GO_0003779Molecular functionactin binding
GO_0008270Molecular functionzinc ion binding
GO_0031267Molecular functionsmall GTPase binding

IV. Literature review

[source]
Gene nameMYRIP
Protein nameRab effector MyRIP (Exophilin-8) (Myosin-VIIa- and Rab-interacting protein) (Synaptotagmin-like protein lacking C2 domains C) (SlaC2-c) (Slp homolog lacking C2 domains c)
Myosin VIIA and Rab interacting protein
SynonymsSLAC2C
DescriptionFUNCTION: Rab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the motor proteins MYO5A and MYO7A. May link RAB27A-containing vesicles to actin filaments. Functions as a protein kinase A-anchoring protein (AKAP). May act as a scaffolding protein that links PKA to components of the exocytosis machinery, thus facilitating exocytosis, including insulin release (By similarity). .

AccessionsF8WFC5
Q8NFW9
ENST00000458292.5 [Q8NFW9-5]
ENST00000396217.7 [Q8NFW9-6]
ENST00000539167.2 [Q8NFW9-4]
ENST00000458441.5
ENST00000444716.5 [Q8NFW9-1]
ENST00000425621.5 [Q8NFW9-2]
ENST00000302541.11 [Q8NFW9-1]