MYOZ1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of MYOZ1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of MYOZ1 at tissue level.

III. Associated gene sets

GO_0007519Biological processskeletal muscle tissue development
GO_0070885Biological processnegative regulation of calcineurin-NFAT signaling cascade
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0043417Biological processnegative regulation of skeletal muscle tissue regeneration
GO_0042060Biological processwound healing
GO_0030239Biological processmyofibril assembly
GO_0043503Biological processskeletal muscle fiber adaptation
GO_0045214Biological processsarcomere organization
GO_0030018Cellular componentZ disc
GO_0015629Cellular componentactin cytoskeleton
GO_0031143Cellular componentpseudopodium
GO_0005634Cellular componentnucleus
GO_0004865Molecular functionprotein serine/threonine phosphatase inhibitor activity
GO_0051373Molecular functionFATZ binding
GO_0031433Molecular functiontelethonin binding
GO_0140693Molecular functionmolecular condensate scaffold activity
GO_0042805Molecular functionactinin binding
GO_0005515Molecular functionprotein binding
GO_0003779Molecular functionactin binding

IV. Literature review

[source]
Gene nameMYOZ1
Protein nameMyozenin-1 (Calsarcin-2) (Filamin-, actinin- and telethonin-binding protein) (Protein FATZ)
SynonymsMYOZ
DescriptionFUNCTION: Myozenins may serve as intracellular binding proteins involved in linking Z-disk proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis.

AccessionsQ9NP98
ENST00000359322.5