MYO3B | OmnibusX

Name	Number of supported studies	Average coverage
eye	3 studies	41% ± 14%	Explore
brain	3 studies	21% ± 8%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	100%	181.27	652 / 653	82%	3.46	496 / 605
kidney	100%	365.49	89 / 89	18%	1.06	166 / 901
pancreas	95%	73.16	313 / 328	11%	0.26	19 / 178
bladder	76%	71.76	16 / 21	26%	1.22	132 / 504
ureter	0%	0	0 / 0	100%	5.58	1 / 1
skin	84%	72.68	1511 / 1809	5%	0.12	24 / 472
uterus	48%	27.54	81 / 170	34%	1.38	154 / 459
breast	52%	19.90	240 / 459	24%	3.00	271 / 1118
ovary	8%	2.86	14 / 180	66%	2.73	283 / 430
prostate	64%	25.56	156 / 245	3%	0.07	14 / 502
esophagus	44%	22.39	633 / 1445	16%	0.63	30 / 183
lung	22%	5.52	127 / 578	29%	1.25	332 / 1155
brain	41%	20.82	1086 / 2642	7%	0.16	46 / 705
blood vessel	44%	112.53	581 / 1335	0%	0	0 / 0
tonsil	0%	0	0 / 0	38%	1.04	17 / 45
intestine	27%	11.23	261 / 966	6%	0.28	32 / 527
peripheral blood	33%	108.97	305 / 929	0%	0	0 / 0
spleen	28%	16.15	68 / 241	0%	0	0 / 0
adipose	25%	10.01	303 / 1204	0%	0	0 / 0
muscle	15%	5.28	122 / 803	0%	0	0 / 0
stomach	8%	1.86	29 / 359	6%	0.30	17 / 286
lymph node	0%	0	0 / 0	14%	0.29	4 / 29
liver	8%	2.30	17 / 226	4%	0.13	17 / 406
heart	5%	1.12	41 / 861	0%	0	0 / 0
adrenal gland	2%	0.60	6 / 258	2%	0.03	5 / 230
eye	0%	0	0 / 0	1%	0.03	1 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0007601	Biological process	visual perception
GO_0007605	Biological process	sensory perception of sound
GO_0030832	Biological process	regulation of actin filament length
GO_0018105	Biological process	peptidyl-serine phosphorylation
GO_0051491	Biological process	positive regulation of filopodium assembly
GO_0090103	Biological process	cochlea morphogenesis
GO_0032433	Cellular component	filopodium tip
GO_0001917	Cellular component	photoreceptor inner segment
GO_0032426	Cellular component	stereocilium tip
GO_0016459	Cellular component	myosin complex
GO_0005737	Cellular component	cytoplasm
GO_0000146	Molecular function	microfilament motor activity
GO_0004674	Molecular function	protein serine/threonine kinase activity
GO_0005515	Molecular function	protein binding
GO_0003779	Molecular function	actin binding
GO_0106310	Molecular function	protein serine kinase activity
GO_0005524	Molecular function	ATP binding

Gene name	MYO3B
Protein name	Uncharacterized protein MYO3B Myosin-IIIb (EC 2.7.11.1) non-specific serine/threonine protein kinase (EC 2.7.11.1) Myosin IIIB
Synonyms	hCG_2036976
Description	FUNCTION: Probable actin-based motor with a protein kinase activity. Required for normal cochlear hair bundle development and hearing. Plays an important role in the early steps of cochlear hair bundle morphogenesis. Influences the number and lengths of stereocilia to be produced and limits the growth of microvilli within the forming auditory hair bundles thereby contributing to the architecture of the hair bundle, including its staircase pattern. Involved in the elongation of actin in stereocilia tips by transporting the actin regulatory factor ESPN to the plus ends of actin filaments. .
Accessions	ENST00000442690.1 ENST00000408978.9 [Q8WXR4-1] ENST00000409044.7 [Q8WXR4-4] Q8WXR4 F5H2J1 H7C1M9 Q53R82 ENST00000484338.6 B7ZM71 ENST00000317935.10 [Q8WXR4-3]

MYO3B report