MTURN report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0045654Biological processpositive regulation of megakaryocyte differentiation
GO_0070374Biological processpositive regulation of ERK1 and ERK2 cascade
GO_0032088Biological processnegative regulation of NF-kappaB transcription factor activity
GO_0023051Biological processregulation of signaling
GO_0046330Biological processpositive regulation of JNK cascade
GO_0005737Cellular componentcytoplasm
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameMTURN
Protein nameMaturin
Maturin (Maturin neural progenitor differentiation regulator protein homolog) (Protein Ells1)
SynonymsC7orf41
DescriptionFUNCTION: Promotes megakaryocyte differentiation by enhancing ERK and JNK signaling as well as up-regulating RUNX1 and FLI1 expression . Represses NF-kappa-B transcriptional activity by inhibiting phosphorylation of RELA at 'Ser-536' . May be involved in early neuronal development (By similarity). .

AccessionsENST00000324453.13 [Q8N3F0-1]
Q8N3F0
C9JBT1
ENST00000324489.5 [Q8N3F0-3]
ENST00000434060.1
ENST00000409688.1 [Q8N3F0-4]