Name | Number of supported studies | Average coverage | |
---|---|---|---|
glutamatergic neuron | 8 studies | 48% ± 23% | |
Mueller cell | 5 studies | 43% ± 22% | |
GABAergic neuron | 5 studies | 52% ± 16% | |
interneuron | 5 studies | 39% ± 22% | |
oligodendrocyte precursor cell | 4 studies | 24% ± 7% | |
neuron | 3 studies | 21% ± 3% | |
smooth muscle cell | 3 studies | 25% ± 9% | |
endothelial cell | 3 studies | 22% ± 3% | |
retinal bipolar neuron | 3 studies | 31% ± 14% | |
OFF-bipolar cell | 3 studies | 27% ± 16% | |
ON-bipolar cell | 3 studies | 32% ± 17% | |
retinal cone cell | 3 studies | 40% ± 16% | |
retinal rod cell | 3 studies | 59% ± 16% | |
rod bipolar cell | 3 studies | 45% ± 18% | |
retinal pigment epithelial cell | 3 studies | 32% ± 10% | |
astrocyte | 3 studies | 21% ± 5% | |
oligodendrocyte | 3 studies | 20% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 96% | 2231.05 | 1384 / 1445 | 93% | 11.71 | 170 / 183 |
bladder | 100% | 3162.67 | 21 / 21 | 78% | 7.26 | 393 / 504 |
brain | 89% | 9099.98 | 2352 / 2642 | 86% | 4.84 | 609 / 705 |
pancreas | 84% | 730.96 | 276 / 328 | 81% | 4.66 | 144 / 178 |
stomach | 90% | 2811.32 | 322 / 359 | 73% | 5.37 | 208 / 286 |
intestine | 91% | 5534.00 | 882 / 966 | 68% | 4.83 | 360 / 527 |
uterus | 68% | 601.57 | 115 / 170 | 74% | 5.87 | 339 / 459 |
kidney | 58% | 455.39 | 52 / 89 | 83% | 7.78 | 747 / 901 |
skin | 85% | 1466.48 | 1546 / 1809 | 49% | 2.63 | 231 / 472 |
prostate | 77% | 618.08 | 188 / 245 | 52% | 1.92 | 263 / 502 |
breast | 59% | 427.08 | 269 / 459 | 68% | 4.88 | 758 / 1118 |
lung | 55% | 352.80 | 320 / 578 | 66% | 5.53 | 757 / 1155 |
tonsil | 0% | 0 | 0 / 0 | 82% | 5.07 | 37 / 45 |
adrenal gland | 12% | 129.56 | 30 / 258 | 66% | 10.96 | 151 / 230 |
ovary | 42% | 242.37 | 75 / 180 | 16% | 0.68 | 69 / 430 |
heart | 54% | 381.36 | 469 / 861 | 0% | 0 | 0 / 0 |
liver | 21% | 122.69 | 48 / 226 | 23% | 3.15 | 95 / 406 |
lymph node | 0% | 0 | 0 / 0 | 38% | 1.73 | 11 / 29 |
adipose | 35% | 262.50 | 423 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 29% | 194.70 | 389 / 1335 | 0% | 0 | 0 / 0 |
muscle | 24% | 127.20 | 194 / 803 | 0% | 0 | 0 / 0 |
thymus | 1% | 7.13 | 9 / 653 | 16% | 2.45 | 98 / 605 |
eye | 0% | 0 | 0 / 0 | 15% | 0.75 | 12 / 80 |
spleen | 8% | 37.23 | 19 / 241 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0001578 | Biological process | microtubule bundle formation |
GO_0007059 | Biological process | chromosome segregation |
GO_0051301 | Biological process | cell division |
GO_0010506 | Biological process | regulation of autophagy |
GO_0090314 | Biological process | positive regulation of protein targeting to membrane |
GO_0045197 | Biological process | establishment or maintenance of epithelial cell apical/basal polarity |
GO_0016324 | Cellular component | apical plasma membrane |
GO_0005615 | Cellular component | extracellular space |
GO_0005876 | Cellular component | spindle microtubule |
GO_0030496 | Cellular component | midbody |
GO_0005856 | Cellular component | cytoskeleton |
GO_0000922 | Cellular component | spindle pole |
GO_0000776 | Cellular component | kinetochore |
GO_0097427 | Cellular component | microtubule bundle |
GO_0016328 | Cellular component | lateral plasma membrane |
GO_0005737 | Cellular component | cytoplasm |
GO_0016327 | Cellular component | apicolateral plasma membrane |
GO_0042803 | Molecular function | protein homodimerization activity |
GO_0008017 | Molecular function | microtubule binding |
GO_0003723 | Molecular function | RNA binding |
GO_0005515 | Molecular function | protein binding |
Gene name | MTCL1 |
Protein name | Microtubule cross-linking factor 1 (Coiled-coil domain-containing protein 165) (PAR-1-interacting protein) (SOGA family member 2) Microtubule crosslinking factor 1 |
Synonyms | SOGA2 CCDC165 KIAA0802 |
Description | FUNCTION: Microtubule-associated factor involved in the late phase of epithelial polarization and microtubule dynamics regulation . Plays a role in the development and maintenance of non-centrosomal microtubule bundles at the lateral membrane in polarized epithelial cells . Required for faithful chromosome segregation during mitosis . . |
Accessions | J3QLE1 ENST00000306329.16 [Q9Y4B5-1] ENST00000523122.1 Q9Y4B5 ENST00000517570.5 [Q9Y4B5-2] ENST00000695635.1 ENST00000695636.1 ENST00000520495.5 A0A8Q3SIW6 A0A8Q3WKN6 J3QL92 ENST00000359865.7 [Q9Y4B5-3] |