MTCL1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0001578Biological processmicrotubule bundle formation
GO_0007059Biological processchromosome segregation
GO_0051301Biological processcell division
GO_0010506Biological processregulation of autophagy
GO_0090314Biological processpositive regulation of protein targeting to membrane
GO_0045197Biological processestablishment or maintenance of epithelial cell apical/basal polarity
GO_0016324Cellular componentapical plasma membrane
GO_0005615Cellular componentextracellular space
GO_0005876Cellular componentspindle microtubule
GO_0030496Cellular componentmidbody
GO_0005856Cellular componentcytoskeleton
GO_0000922Cellular componentspindle pole
GO_0000776Cellular componentkinetochore
GO_0097427Cellular componentmicrotubule bundle
GO_0016328Cellular componentlateral plasma membrane
GO_0005737Cellular componentcytoplasm
GO_0016327Cellular componentapicolateral plasma membrane
GO_0042803Molecular functionprotein homodimerization activity
GO_0008017Molecular functionmicrotubule binding
GO_0003723Molecular functionRNA binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameMTCL1
Protein nameMicrotubule cross-linking factor 1 (Coiled-coil domain-containing protein 165) (PAR-1-interacting protein) (SOGA family member 2)
Microtubule crosslinking factor 1
SynonymsSOGA2
CCDC165
KIAA0802
DescriptionFUNCTION: Microtubule-associated factor involved in the late phase of epithelial polarization and microtubule dynamics regulation . Plays a role in the development and maintenance of non-centrosomal microtubule bundles at the lateral membrane in polarized epithelial cells . Required for faithful chromosome segregation during mitosis . .

AccessionsJ3QLE1
ENST00000306329.16 [Q9Y4B5-1]
ENST00000523122.1
Q9Y4B5
ENST00000517570.5 [Q9Y4B5-2]
ENST00000695635.1
ENST00000695636.1
ENST00000520495.5
A0A8Q3SIW6
A0A8Q3WKN6
J3QL92
ENST00000359865.7 [Q9Y4B5-3]