Name | Number of supported studies | Average coverage | |
---|---|---|---|
macrophage | 41 studies | 45% ± 17% | |
microglial cell | 15 studies | 36% ± 14% | |
myeloid cell | 12 studies | 43% ± 18% | |
non-classical monocyte | 9 studies | 22% ± 6% | |
alveolar macrophage | 8 studies | 72% ± 9% | |
monocyte | 7 studies | 40% ± 24% | |
dendritic cell | 6 studies | 37% ± 12% | |
mononuclear phagocyte | 4 studies | 39% ± 19% | |
conventional dendritic cell | 4 studies | 29% ± 9% | |
tissue-resident macrophage | 3 studies | 51% ± 7% | |
retinal cone cell | 3 studies | 73% ± 27% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 93% | 1215.54 | 426 / 459 | 96% | 22.53 | 1072 / 1118 |
lung | 100% | 6961.62 | 577 / 578 | 85% | 20.23 | 987 / 1155 |
bladder | 100% | 614.38 | 21 / 21 | 55% | 7.83 | 275 / 504 |
kidney | 62% | 394.82 | 55 / 89 | 83% | 20.56 | 749 / 901 |
ovary | 51% | 287.90 | 92 / 180 | 83% | 11.77 | 357 / 430 |
intestine | 84% | 533.85 | 811 / 966 | 50% | 7.00 | 264 / 527 |
adrenal gland | 95% | 1475.70 | 245 / 258 | 36% | 2.92 | 82 / 230 |
pancreas | 45% | 228.09 | 149 / 328 | 84% | 15.62 | 150 / 178 |
thymus | 59% | 317.28 | 386 / 653 | 61% | 6.00 | 371 / 605 |
stomach | 49% | 262.38 | 176 / 359 | 63% | 9.07 | 181 / 286 |
uterus | 56% | 285.05 | 95 / 170 | 55% | 5.81 | 252 / 459 |
esophagus | 53% | 322.37 | 770 / 1445 | 56% | 5.68 | 103 / 183 |
prostate | 62% | 306.08 | 153 / 245 | 38% | 2.74 | 191 / 502 |
brain | 34% | 231.76 | 891 / 2642 | 66% | 15.94 | 467 / 705 |
adipose | 98% | 2747.49 | 1175 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 95% | 1815.92 | 1263 / 1335 | 0% | 0 | 0 / 0 |
skin | 22% | 95.86 | 404 / 1809 | 70% | 11.57 | 329 / 472 |
spleen | 91% | 1674.62 | 219 / 241 | 0% | 0 | 0 / 0 |
liver | 36% | 236.24 | 81 / 226 | 36% | 3.24 | 145 / 406 |
peripheral blood | 56% | 431.72 | 520 / 929 | 0% | 0 | 0 / 0 |
heart | 53% | 368.93 | 457 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 42% | 5.12 | 19 / 45 |
lymph node | 0% | 0 | 0 / 0 | 34% | 4.74 | 10 / 29 |
eye | 0% | 0 | 0 / 0 | 11% | 0.75 | 9 / 80 |
muscle | 10% | 35.60 | 83 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0010744 | Biological process | positive regulation of macrophage derived foam cell differentiation |
GO_0010629 | Biological process | negative regulation of gene expression |
GO_0006898 | Biological process | receptor-mediated endocytosis |
GO_0034381 | Biological process | plasma lipoprotein particle clearance |
GO_0010886 | Biological process | positive regulation of cholesterol storage |
GO_0051649 | Biological process | establishment of localization in cell |
GO_0006911 | Biological process | phagocytosis, engulfment |
GO_0097242 | Biological process | amyloid-beta clearance |
GO_0042953 | Biological process | lipoprotein transport |
GO_0071407 | Biological process | cellular response to organic cyclic compound |
GO_0030301 | Biological process | cholesterol transport |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0030666 | Cellular component | endocytic vesicle membrane |
GO_0034362 | Cellular component | low-density lipoprotein particle |
GO_0005581 | Cellular component | collagen trimer |
GO_0038024 | Molecular function | cargo receptor activity |
GO_0001540 | Molecular function | amyloid-beta binding |
GO_0005044 | Molecular function | scavenger receptor activity |
GO_0030169 | Molecular function | low-density lipoprotein particle binding |
GO_0005515 | Molecular function | protein binding |
Gene name | MSR1 |
Protein name | Macrophage scavenger receptor 1 Macrophage scavenger receptor 1 (cDNA FLJ55770, highly similar to Macrophage scavenger receptor types I and II) Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II) (Scavenger receptor class A member 1) (CD antigen CD204) |
Synonyms | SCARA1 |
Description | FUNCTION: Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL) . Isoform III does not internalize acetylated LDL . . |
Accessions | ENST00000445506.6 ENST00000350896.3 [P21757-3] E5RFW8 ENST00000381998.8 [P21757-2] B4DDJ5 ENST00000518960.5 ENST00000519060.6 ENST00000522672.5 ENST00000262101.10 [P21757-1] ENST00000518026.5 P21757 H0YBY2 E5RI91 E5RFI4 ENST00000355282.6 [P21757-3] |