Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| macrophage | 7 studies | 28% ± 12% | |
| classical monocyte | 6 studies | 21% ± 6% | |
| conventional dendritic cell | 6 studies | 32% ± 12% | |
| plasmacytoid dendritic cell | 6 studies | 23% ± 6% | |
| fibroblast | 5 studies | 26% ± 10% | |
| natural killer cell | 5 studies | 20% ± 4% | |
| endothelial cell | 5 studies | 25% ± 10% | |
| non-classical monocyte | 4 studies | 19% ± 3% | |
| myeloid cell | 4 studies | 19% ± 5% | |
| epithelial cell | 4 studies | 41% ± 8% | |
| myofibroblast cell | 4 studies | 18% ± 2% | |
| ciliated cell | 4 studies | 22% ± 3% | |
| dendritic cell | 4 studies | 35% ± 5% | |
| regulatory T cell | 4 studies | 19% ± 3% | |
| oligodendrocyte precursor cell | 4 studies | 22% ± 7% | |
| pancreatic A cell | 3 studies | 39% ± 17% | |
| type B pancreatic cell | 3 studies | 37% ± 19% | |
| hematopoietic precursor cell | 3 studies | 23% ± 4% | |
| CD16-negative, CD56-bright natural killer cell, human | 3 studies | 16% ± 1% | |
| B cell | 3 studies | 19% ± 4% | |
| GABAergic neuron | 3 studies | 36% ± 8% | |
| glutamatergic neuron | 3 studies | 41% ± 11% | |
| connective tissue cell | 3 studies | 23% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| adrenal gland | 100% | 4756.87 | 258 / 258 | 100% | 31.40 | 230 / 230 |
| esophagus | 100% | 1922.72 | 1445 / 1445 | 100% | 26.16 | 183 / 183 |
| ovary | 100% | 2161.14 | 180 / 180 | 100% | 42.69 | 430 / 430 |
| prostate | 100% | 2163.02 | 245 / 245 | 100% | 26.19 | 502 / 502 |
| skin | 100% | 2353.90 | 1809 / 1809 | 100% | 50.67 | 472 / 472 |
| stomach | 100% | 1386.30 | 359 / 359 | 100% | 24.90 | 286 / 286 |
| thymus | 100% | 2809.10 | 653 / 653 | 100% | 45.99 | 605 / 605 |
| brain | 100% | 2342.11 | 2641 / 2642 | 100% | 41.16 | 705 / 705 |
| lung | 100% | 2208.98 | 578 / 578 | 100% | 30.40 | 1154 / 1155 |
| intestine | 100% | 1782.27 | 966 / 966 | 100% | 23.27 | 526 / 527 |
| bladder | 100% | 2335.52 | 21 / 21 | 100% | 26.23 | 503 / 504 |
| kidney | 100% | 2224.91 | 89 / 89 | 100% | 35.78 | 898 / 901 |
| breast | 100% | 2157.64 | 459 / 459 | 100% | 31.48 | 1114 / 1118 |
| uterus | 100% | 2163.42 | 170 / 170 | 100% | 27.59 | 457 / 459 |
| pancreas | 100% | 1290.27 | 328 / 328 | 99% | 22.94 | 176 / 178 |
| liver | 99% | 1045.46 | 224 / 226 | 90% | 14.31 | 365 / 406 |
| adipose | 100% | 2002.03 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 72.44 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 30.86 | 29 / 29 |
| spleen | 100% | 2361.85 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 20.22 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 13.88 | 1 / 1 |
| blood vessel | 100% | 1853.80 | 1332 / 1335 | 0% | 0 | 0 / 0 |
| heart | 99% | 1645.92 | 851 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 94% | 1366.62 | 875 / 929 | 0% | 0 | 0 / 0 |
| muscle | 91% | 612.27 | 729 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0042592 | Biological process | homeostatic process |
| GO_2000377 | Biological process | regulation of reactive oxygen species metabolic process |
| GO_0034614 | Biological process | cellular response to reactive oxygen species |
| GO_0048839 | Biological process | inner ear development |
| GO_1901858 | Biological process | regulation of mitochondrial DNA metabolic process |
| GO_0000002 | Biological process | mitochondrial genome maintenance |
| GO_0032836 | Biological process | glomerular basement membrane development |
| GO_0055085 | Biological process | transmembrane transport |
| GO_0005778 | Cellular component | peroxisomal membrane |
| GO_0005743 | Cellular component | mitochondrial inner membrane |
| GO_0005829 | Cellular component | cytosol |
| GO_0005777 | Cellular component | peroxisome |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0015267 | Molecular function | channel activity |
| Gene name | MPV17 |
| Protein name | Mitochondrial inner membrane protein MPV17 (MpV17 mitochondrial inner membrane protein isoform 2) MpV17 mitochondrial inner membrane protein isoform 4 Mpv17 protein Mitochondrial inner membrane protein MPV17 Protein Mpv17 |
| Synonyms | hCG_23713 |
| Description | FUNCTION: Non-selective channel that modulates the membrane potential under normal conditions and oxidative stress, and is involved in mitochondrial homeostasis . Involved in mitochondrial deoxynucleoside triphosphates (dNTP) pool homeostasis and mitochondrial DNA (mtDNA) maintenance . May be involved in the regulation of reactive oxygen species metabolism and the control of oxidative phosphorylation (By similarity). . |
| Accessions | ENST00000399052.8 G5E9F5 H0Y6M5 A0A0S2Z469 E7EX18 P39210 ENST00000402310.5 ENST00000357186.10 ENST00000428910.5 ENST00000403262.6 ENST00000415514.5 A0A0S2Z466 A8MTD3 Q9UPC7 B5MC10 ENST00000405076.5 ENST00000402722.5 ENST00000430991.5 ENST00000380044.6 C9J473 A0A0S2Z3Z9 A8MPV4 ENST00000426513.6 ENST00000405983.5 B5MCF8 B5MC53 F8WEL3 ENST00000233545.6 |