METTL21A report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006479Biological processprotein methylation
GO_0043462Biological processregulation of ATP-dependent activity
GO_0006338Biological processchromatin remodeling
GO_0018022Biological processpeptidyl-lysine methylation
GO_0032991Cellular componentprotein-containing complex
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0008276Molecular functionprotein methyltransferase activity
GO_0030544Molecular functionHsp70 protein binding
GO_0042054Molecular functionhistone methyltransferase activity
GO_0031072Molecular functionheat shock protein binding
GO_0005515Molecular functionprotein binding
GO_0016279Molecular functionprotein-lysine N-methyltransferase activity
GO_0051117Molecular functionATPase binding

IV. Literature review

[source]
Gene nameMETTL21A
Protein nameProtein N-lysine methyltransferase METTL21A (EC 2.1.1.-) (HSPA lysine methyltransferase) (HSPA-KMT) (Hepatocellular carcinoma-associated antigen 557b) (Methyltransferase-like protein 21A)
Protein N-lysine methyltransferase METTL21A (Methyltransferase-like protein 21A)
Methyltransferase 21A, HSPA lysine
SynonymsHCA557B
hCG_15462
FAM119A
LOC151194
DescriptionFUNCTION: Protein-lysine methyltransferase that selectively trimethylates residues in heat shock protein 70 (HSP70) family members. Contributes to the in vivo trimethylation of Lys residues in HSPA1 and HSPA8. In vitro methylates 'Lys-561' in HSPA1, 'Lys-564' in HSPA2, 'Lys-585' in HSPA5, 'Lys-563' in HSPA6 and 'Lys-561' in HSPA8. .

AccessionsH7BXH9
ENST00000448007.6 [Q8WXB1-1]
C9JSX1
ENST00000406927.6 [Q8WXB1-1]
ENST00000442521.1 [Q8WXB1-1]
C9JES0
Q8WXB1
ENST00000448823.2
ENST00000426075.5 [Q8WXB1-1]
ENST00000432416.5
ENST00000458426.5 [Q8WXB1-2]
ENST00000411432.6 [Q8WXB1-1]
ENST00000272839.7
ENST00000425132.5 [Q8WXB1-2]