Name | Number of supported studies | Average coverage | |
---|---|---|---|
B cell | 9 studies | 21% ± 6% | |
mast cell | 5 studies | 24% ± 9% | |
macrophage | 5 studies | 20% ± 7% | |
endothelial cell | 4 studies | 22% ± 3% | |
glutamatergic neuron | 4 studies | 37% ± 11% | |
microglial cell | 4 studies | 23% ± 7% | |
naive B cell | 4 studies | 22% ± 5% | |
astrocyte | 4 studies | 21% ± 4% | |
conventional dendritic cell | 3 studies | 23% ± 6% | |
epithelial cell | 3 studies | 36% ± 4% | |
precursor B cell | 3 studies | 18% ± 1% | |
GABAergic neuron | 3 studies | 33% ± 5% | |
dendritic cell | 3 studies | 25% ± 7% | |
leukocyte | 3 studies | 17% ± 1% | |
neuron | 3 studies | 19% ± 3% | |
plasmacytoid dendritic cell | 3 studies | 20% ± 4% | |
oligodendrocyte | 3 studies | 18% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
stomach | 100% | 429.14 | 359 / 359 | 100% | 6.78 | 286 / 286 |
brain | 100% | 707.17 | 2641 / 2642 | 100% | 7.61 | 705 / 705 |
lung | 100% | 527.61 | 578 / 578 | 100% | 7.75 | 1153 / 1155 |
breast | 100% | 489.65 | 459 / 459 | 100% | 6.69 | 1114 / 1118 |
ovary | 100% | 583.70 | 180 / 180 | 100% | 8.42 | 428 / 430 |
thymus | 100% | 782.76 | 653 / 653 | 99% | 8.88 | 600 / 605 |
prostate | 100% | 497.29 | 245 / 245 | 99% | 5.69 | 497 / 502 |
intestine | 100% | 549.64 | 966 / 966 | 99% | 6.81 | 521 / 527 |
uterus | 100% | 542.06 | 170 / 170 | 98% | 6.62 | 451 / 459 |
pancreas | 100% | 339.16 | 327 / 328 | 98% | 5.25 | 175 / 178 |
esophagus | 100% | 443.69 | 1445 / 1445 | 98% | 6.39 | 179 / 183 |
bladder | 100% | 418.43 | 21 / 21 | 98% | 5.87 | 492 / 504 |
liver | 100% | 400.69 | 226 / 226 | 98% | 5.37 | 396 / 406 |
skin | 99% | 309.78 | 1786 / 1809 | 98% | 7.36 | 464 / 472 |
kidney | 100% | 510.49 | 89 / 89 | 96% | 5.37 | 868 / 901 |
adrenal gland | 100% | 538.64 | 258 / 258 | 90% | 4.25 | 207 / 230 |
adipose | 100% | 559.19 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 11.37 | 29 / 29 |
spleen | 100% | 848.34 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 6.03 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 5.14 | 1 / 1 |
muscle | 100% | 392.78 | 801 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 99% | 351.39 | 1328 / 1335 | 0% | 0 | 0 / 0 |
heart | 99% | 431.88 | 851 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 96% | 522.29 | 894 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 83% | 3.29 | 66 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006479 | Biological process | protein methylation |
GO_0043462 | Biological process | regulation of ATP-dependent activity |
GO_0006338 | Biological process | chromatin remodeling |
GO_0018022 | Biological process | peptidyl-lysine methylation |
GO_0032991 | Cellular component | protein-containing complex |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0008276 | Molecular function | protein methyltransferase activity |
GO_0030544 | Molecular function | Hsp70 protein binding |
GO_0042054 | Molecular function | histone methyltransferase activity |
GO_0031072 | Molecular function | heat shock protein binding |
GO_0005515 | Molecular function | protein binding |
GO_0016279 | Molecular function | protein-lysine N-methyltransferase activity |
GO_0051117 | Molecular function | ATPase binding |
Gene name | METTL21A |
Protein name | Protein N-lysine methyltransferase METTL21A (EC 2.1.1.-) (HSPA lysine methyltransferase) (HSPA-KMT) (Hepatocellular carcinoma-associated antigen 557b) (Methyltransferase-like protein 21A) Protein N-lysine methyltransferase METTL21A (Methyltransferase-like protein 21A) Methyltransferase 21A, HSPA lysine |
Synonyms | HCA557B hCG_15462 FAM119A LOC151194 |
Description | FUNCTION: Protein-lysine methyltransferase that selectively trimethylates residues in heat shock protein 70 (HSP70) family members. Contributes to the in vivo trimethylation of Lys residues in HSPA1 and HSPA8. In vitro methylates 'Lys-561' in HSPA1, 'Lys-564' in HSPA2, 'Lys-585' in HSPA5, 'Lys-563' in HSPA6 and 'Lys-561' in HSPA8. . |
Accessions | H7BXH9 ENST00000448007.6 [Q8WXB1-1] C9JSX1 ENST00000406927.6 [Q8WXB1-1] ENST00000442521.1 [Q8WXB1-1] C9JES0 Q8WXB1 ENST00000448823.2 ENST00000426075.5 [Q8WXB1-1] ENST00000432416.5 ENST00000458426.5 [Q8WXB1-2] ENST00000411432.6 [Q8WXB1-1] ENST00000272839.7 ENST00000425132.5 [Q8WXB1-2] |