Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| ciliated cell | 6 studies | 22% ± 6% | |
| endothelial cell of vascular tree | 6 studies | 23% ± 4% | |
| endothelial cell | 5 studies | 22% ± 9% | |
| epithelial cell | 5 studies | 31% ± 14% | |
| glutamatergic neuron | 4 studies | 33% ± 13% | |
| club cell | 3 studies | 25% ± 7% | |
| duct epithelial cell | 3 studies | 20% ± 6% | |
| respiratory goblet cell | 3 studies | 30% ± 20% | |
| GABAergic neuron | 3 studies | 33% ± 8% | |
| basal cell | 3 studies | 25% ± 1% | |
| astrocyte | 3 studies | 19% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 4853.99 | 1445 / 1445 | 100% | 61.26 | 183 / 183 |
| skin | 100% | 5596.80 | 1809 / 1809 | 100% | 50.14 | 471 / 472 |
| prostate | 100% | 5652.77 | 245 / 245 | 100% | 35.40 | 500 / 502 |
| lung | 100% | 8101.58 | 578 / 578 | 100% | 43.01 | 1150 / 1155 |
| thymus | 100% | 5717.64 | 653 / 653 | 100% | 36.24 | 602 / 605 |
| bladder | 100% | 4683.67 | 21 / 21 | 99% | 45.22 | 501 / 504 |
| brain | 99% | 4680.25 | 2626 / 2642 | 100% | 61.57 | 705 / 705 |
| breast | 100% | 5492.92 | 459 / 459 | 99% | 63.65 | 1111 / 1118 |
| uterus | 100% | 6912.94 | 170 / 170 | 99% | 51.77 | 456 / 459 |
| ovary | 100% | 6427.02 | 180 / 180 | 99% | 35.96 | 427 / 430 |
| stomach | 100% | 4562.05 | 359 / 359 | 99% | 59.69 | 284 / 286 |
| intestine | 100% | 5367.21 | 966 / 966 | 99% | 54.95 | 523 / 527 |
| kidney | 100% | 4902.21 | 89 / 89 | 99% | 33.65 | 891 / 901 |
| pancreas | 100% | 2828.06 | 328 / 328 | 99% | 36.31 | 176 / 178 |
| liver | 100% | 2755.44 | 226 / 226 | 98% | 27.63 | 396 / 406 |
| adrenal gland | 100% | 5448.92 | 258 / 258 | 97% | 26.22 | 223 / 230 |
| adipose | 100% | 4855.44 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 49.05 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 41.77 | 29 / 29 |
| muscle | 100% | 8141.23 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 5822.48 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 43.61 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 18.94 | 1 / 1 |
| blood vessel | 100% | 4149.60 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| heart | 99% | 4008.01 | 851 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 78% | 2404.44 | 723 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0051123 | Biological process | RNA polymerase II preinitiation complex assembly |
| GO_0060261 | Biological process | positive regulation of transcription initiation by RNA polymerase II |
| GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
| GO_0032968 | Biological process | positive regulation of transcription elongation by RNA polymerase II |
| GO_0016592 | Cellular component | mediator complex |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0070847 | Cellular component | core mediator complex |
| GO_0005634 | Cellular component | nucleus |
| GO_0046966 | Molecular function | nuclear thyroid hormone receptor binding |
| GO_0003713 | Molecular function | transcription coactivator activity |
| GO_0042809 | Molecular function | nuclear vitamin D receptor binding |
| GO_0030374 | Molecular function | nuclear receptor coactivator activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0003712 | Molecular function | transcription coregulator activity |
| Gene name | MED24 |
| Protein name | Mediator complex subunit MED24 variant MED24_i10 Mediator of RNA polymerase II transcription subunit 24 (Mediator complex subunit 24) Mediator of RNA polymerase II transcription subunit 24 (Activator-recruited cofactor 100 kDa component) (ARC100) (Cofactor required for Sp1 transcriptional activation subunit 4) (CRSP complex subunit 4) (Mediator complex subunit 24) (Thyroid hormone receptor-associated protein 4) (Thyroid hormone receptor-associated protein complex 100 kDa component) (Trap100) (hTRAP100) (Vitamin D3 receptor-interacting protein complex 100 kDa component) (DRIP100) Mediator complex subunit 24 |
| Synonyms | DRIP100 hCG_30017 KIAA0130 THRAP4 TRAP100 CRSP4 ARC100 |
| Description | FUNCTION: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. . |
| Accessions | ENST00000356271.7 [O75448-2] J3KTL3 B9TX66 ENST00000394127.6 [O75448-2] B9TX65 B9TX69 ENST00000491466.5 H0YEG1 ENST00000428757.6 F5H0M2 B9TX76 B9TX71 ENST00000578161.2 B9TX68 B9TX62 ENST00000537674.6 ENST00000578901.1 ENST00000580517.5 ENST00000422942.6 ENST00000501516.7 F5GY88 ENST00000394126.5 F5H5K2 ENST00000535071.6 J3QRH9 B4DDR8 ENST00000535508.6 O75448 B9TX67 B9TX70 ENST00000582023.5 B9TX63 F5H3E6 J3QLF8 J3QLC2 ENST00000543759.6 J3QLC0 J3KSL1 B9TX64 ENST00000394128.7 [O75448-1] ENST00000581058.5 B9TX75 ENST00000580008.5 ENST00000585306.5 B9TX74 E9PFL1 ENST00000580302.1 ENST00000580885.5 J3QLV7 B9TX73 F5H2D6 B9TX72 J3KSU0 A0A0B4J1W0 |
