Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| macrophage | 21 studies | 26% ± 7% | |
| microglial cell | 10 studies | 30% ± 11% | |
| non-classical monocyte | 9 studies | 25% ± 10% | |
| oligodendrocyte precursor cell | 8 studies | 31% ± 15% | |
| endothelial cell | 7 studies | 29% ± 10% | |
| natural killer cell | 7 studies | 17% ± 1% | |
| monocyte | 7 studies | 24% ± 6% | |
| GABAergic neuron | 7 studies | 36% ± 20% | |
| astrocyte | 7 studies | 32% ± 12% | |
| interneuron | 6 studies | 37% ± 22% | |
| epithelial cell | 6 studies | 34% ± 11% | |
| retinal rod cell | 6 studies | 28% ± 8% | |
| classical monocyte | 5 studies | 26% ± 9% | |
| glutamatergic neuron | 5 studies | 47% ± 21% | |
| myeloid cell | 5 studies | 31% ± 9% | |
| retinal cone cell | 5 studies | 26% ± 6% | |
| dendritic cell | 5 studies | 27% ± 13% | |
| CD16-negative, CD56-bright natural killer cell, human | 4 studies | 19% ± 2% | |
| neuron | 4 studies | 27% ± 7% | |
| B cell | 4 studies | 22% ± 6% | |
| CD8-positive, alpha-beta T cell | 4 studies | 17% ± 2% | |
| oligodendrocyte | 4 studies | 26% ± 7% | |
| plasmacytoid dendritic cell | 4 studies | 21% ± 5% | |
| CD4-positive, alpha-beta T cell | 3 studies | 19% ± 1% | |
| conventional dendritic cell | 3 studies | 34% ± 15% | |
| hematopoietic precursor cell | 3 studies | 21% ± 5% | |
| mast cell | 3 studies | 23% ± 9% | |
| lymphocyte | 3 studies | 17% ± 1% | |
| transit amplifying cell | 3 studies | 24% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 2261.33 | 2641 / 2642 | 100% | 13.81 | 705 / 705 |
| esophagus | 100% | 1981.60 | 1443 / 1445 | 100% | 10.60 | 183 / 183 |
| ovary | 100% | 1623.71 | 180 / 180 | 99% | 8.54 | 427 / 430 |
| lung | 99% | 1911.33 | 574 / 578 | 100% | 10.62 | 1153 / 1155 |
| stomach | 100% | 2639.89 | 359 / 359 | 99% | 12.83 | 283 / 286 |
| breast | 100% | 1587.18 | 459 / 459 | 99% | 9.54 | 1105 / 1118 |
| prostate | 100% | 1885.98 | 244 / 245 | 99% | 8.89 | 498 / 502 |
| thymus | 100% | 1455.44 | 652 / 653 | 99% | 6.73 | 596 / 605 |
| kidney | 100% | 1245.52 | 89 / 89 | 98% | 7.83 | 884 / 901 |
| intestine | 100% | 3183.70 | 966 / 966 | 98% | 11.43 | 517 / 527 |
| bladder | 100% | 2376.33 | 21 / 21 | 97% | 8.67 | 491 / 504 |
| skin | 99% | 1566.01 | 1798 / 1809 | 97% | 11.29 | 460 / 472 |
| uterus | 100% | 1742.83 | 170 / 170 | 97% | 8.04 | 443 / 459 |
| adrenal gland | 100% | 2767.47 | 258 / 258 | 96% | 9.07 | 220 / 230 |
| pancreas | 100% | 1281.43 | 327 / 328 | 96% | 6.04 | 170 / 178 |
| liver | 90% | 801.99 | 204 / 226 | 80% | 4.03 | 324 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 19.82 | 29 / 29 |
| muscle | 100% | 3058.54 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 4135.80 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 8.04 | 45 / 45 |
| blood vessel | 100% | 1781.15 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 100% | 1862.36 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| peripheral blood | 98% | 3938.80 | 914 / 929 | 0% | 0 | 0 / 0 |
| heart | 96% | 3272.49 | 827 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 74% | 3.86 | 59 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_1902031 | Biological process | regulation of NADP metabolic process |
| GO_0006108 | Biological process | malate metabolic process |
| GO_0006090 | Biological process | pyruvate metabolic process |
| GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
| GO_0005759 | Cellular component | mitochondrial matrix |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0004471 | Molecular function | malate dehydrogenase (decarboxylating) (NAD+) activity |
| GO_0004470 | Molecular function | malic enzyme activity |
| GO_0051287 | Molecular function | NAD binding |
| GO_0004473 | Molecular function | malate dehydrogenase (decarboxylating) (NADP+) activity |
| GO_0008948 | Molecular function | oxaloacetate decarboxylase activity |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0009055 | Molecular function | electron transfer activity |
| Gene name | ME2 |
| Protein name | Cadherin NAD-dependent malic enzyme, mitochondrial (NAD-ME) (EC 1.1.1.38) (Malic enzyme 2) Malic enzyme 2 Malic enzyme |
| Synonyms | |
| Description | FUNCTION: NAD-dependent mitochondrial malic enzyme that catalyzes the oxidative decarboxylation of malate to pyruvate. . |
| Accessions | ENST00000638410.1 A0A1W2PRS2 A0A1W2PQF8 A0A1W2PPH1 A0A1W2PQY8 ENST00000640530.1 ENST00000585680.2 A0A1W2PQT3 A0A1W2PPY2 A0A1W2PRY9 A0A1W2PQH3 ENST00000639665.1 ENST00000382927.3 [P23368-2] ENST00000640965.1 A0A1W2PRH1 ENST00000640967.1 ENST00000639850.1 A0A1W2PQ37 A0A1W2PQH4 O15200 ENST00000639398.1 ENST00000639115.1 ENST00000639612.1 P23368 A0A1W2PR68 ENST00000638937.1 ENST00000321341.11 [P23368-1] ENST00000639255.1 ENST00000639688.1 |