MCFD2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0015031Biological processprotein transport
GO_0016192Biological processvesicle-mediated transport
GO_0033116Cellular componentendoplasmic reticulum-Golgi intermediate compartment membrane
GO_0012507Cellular componentER to Golgi transport vesicle membrane
GO_0005794Cellular componentGolgi apparatus
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0005509Molecular functioncalcium ion binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameMCFD2
Protein nameMultiple coagulation factor deficiency protein 2 (Neural stem cell-derived neuronal survival protein)
Multiple coagulation factor deficiency 2, ER cargo receptor complex subunit
SynonymsSDNSF
DescriptionFUNCTION: The MCFD2-LMAN1 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins. Plays a role in the secretion of coagulation factors. .

AccessionsQ8NI22
ENST00000319466.9 [Q8NI22-1]
ENST00000409105.5 [Q8NI22-1]
ENST00000417180.1
A0A3B3IU18
ENST00000409913.5 [Q8NI22-2]
ENST00000409207.5 [Q8NI22-1]
ENST00000409800.5 [Q8NI22-2]
ENST00000444761.6 [Q8NI22-3]
ENST00000649435.1
C9JTR4
ENST00000409147.1 [Q8NI22-2]
H7BZ18
ENST00000409973.5 [Q8NI22-1]
ENST00000434262.1
ENST00000412438.5 [Q8NI22-1]
ENST00000409218.5 [Q8NI22-1]