MBIP report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0046330Biological processpositive regulation of JNK cascade
GO_0010628Biological processpositive regulation of gene expression
GO_0045995Biological processregulation of embryonic development
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0006355Biological processregulation of DNA-templated transcription
GO_0051726Biological processregulation of cell cycle
GO_0051302Biological processregulation of cell division
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0090043Biological processregulation of tubulin deacetylation
GO_0072686Cellular componentmitotic spindle
GO_0005730Cellular componentnucleolus
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0140672Cellular componentATAC complex
GO_0004860Molecular functionprotein kinase inhibitor activity
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameMBIP
Protein nameMAP3K12 binding inhibitory protein 1, isoform CRA_b (cDNA, FLJ96307, Homo sapiens MAP3K12 binding inhibitory protein 1 (MBIP), mRNA)
MAP3K12 binding inhibitory protein 1
MAP3K12-binding inhibitory protein 1 (MAPK upstream kinase-binding inhibitory protein) (MUK-binding inhibitory protein)
SynonymsBM-015
hCG_20993
DescriptionFUNCTION: Inhibits the MAP3K12 activity to induce the activation of the JNK/SAPK pathway. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. .

AccessionsENST00000318473.11 [Q9NS73-5]
ENST00000603139.1
ENST00000604160.1
ENST00000416007.9 [Q9NS73-1]
ENST00000604336.5
ENST00000605579.5
ENST00000359527.11 [Q9NS73-3]
S4R3Y0
B2RCV0
S4R3N2
Q9NS73
S4R2X9
S4R3P6