MAU2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0051301Biological processcell division
GO_0034088Biological processmaintenance of mitotic sister chromatid cohesion
GO_0007059Biological processchromosome segregation
GO_0007064Biological processmitotic sister chromatid cohesion
GO_0090694Cellular componentScc2-Scc4 cohesin loading complex
GO_0016604Cellular componentnuclear body
GO_0005654Cellular componentnucleoplasm
GO_0000785Cellular componentchromatin
GO_0032116Cellular componentSMC loading complex
GO_0005634Cellular componentnucleus
GO_0061775Molecular functioncohesin loader activity
GO_0003690Molecular functiondouble-stranded DNA binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameMAU2
Protein nameMAU2 chromatid cohesion factor homolog (MAU-2) (Cohesin loading complex subunit SCC4 homolog)
MAU2 chromatid cohesion factor homolog (Cohesin loading complex subunit SCC4 homolog)
Cohesin loading complex subunit SCC4 homolog
SynonymsKIAA0892
SCC4
DescriptionFUNCTION: Plays an important role in the loading of the cohesin complex on to DNA. Forms a heterodimeric complex (also known as cohesin loading complex) with NIPBL/SCC2 which mediates the loading of the cohesin complex onto chromatin . Plays a role in sister chromatid cohesion and normal progression through prometaphase . .

AccessionsV9GYS3
Q9Y6X3
ENST00000609122.5
ENST00000262815.13 [Q9Y6X3-1]
ENST00000609060.1
V9GZ52