MARF1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0010468Biological processregulation of gene expression
GO_0006302Biological processdouble-strand break repair
GO_0007143Biological processfemale meiotic nuclear division
GO_0048477Biological processoogenesis
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0005794Cellular componentGolgi apparatus
GO_0005777Cellular componentperoxisome
GO_0016020Cellular componentmembrane
GO_0005737Cellular componentcytoplasm
GO_1905762Molecular functionCCR4-NOT complex binding
GO_0005515Molecular functionprotein binding
GO_0004540Molecular functionRNA nuclease activity
GO_0003674Molecular functionmolecular_function
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameMARF1
Protein nameMeiosis regulator and mRNA stability factor 1 (Limkain-b1)
Meiosis regulator and mRNA stability factor 1
Meiosis regulator and mRNA stability factor 1 (Limkain-b1) (Meiosis arrest female protein 1)
SynonymsKIAA0430
LKAP
DescriptionFUNCTION: Essential regulator of oogenesis required for female meiotic progression to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Probably acts via some RNA metabolic process, equivalent to the piRNA system in males, which mediates the repression of transposable elements during meiosis by forming complexes composed of RNAs and governs the methylation and subsequent repression of transposons. Also required to protect from DNA double-strand breaks (By similarity). .

AccessionsQ9Y4F3
ENST00000549219.1
F8VVB8
ENST00000632465.1 [Q9Y4F3-4]
H0YIB6
F8VRS5
G8JLP4
ENST00000540441.6
ENST00000552553.5
ENST00000633837.1
ENST00000621511.2 [Q9Y4F3-1]
ENST00000551742.5 [Q9Y4F3-5]
ENST00000396368.8 [Q9Y4F3-1]
ENST00000548025.5 [Q9Y4F3-4]
ENST00000633811.1
ENST00000632628.1 [Q9Y4F3-5]
ENST00000633549.1
ENST00000631398.1
ENST00000551878.1