MAP3K6 | OmnibusX

Name	Number of supported studies	Average coverage
capillary endothelial cell	4 studies	22% ± 5%	Explore
glomerular endothelial cell	3 studies	27% ± 3%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of MAP3K6 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
uterus	100%	8028.34	170 / 170	100%	49.39	458 / 459
esophagus	100%	9047.18	1445 / 1445	99%	38.09	182 / 183
prostate	100%	7918.18	245 / 245	99%	21.79	499 / 502
thymus	100%	6904.35	651 / 653	100%	27.95	603 / 605
lung	100%	11963.29	577 / 578	99%	30.12	1138 / 1155
breast	100%	10053.53	459 / 459	98%	23.39	1097 / 1118
skin	97%	10091.60	1756 / 1809	100%	39.32	471 / 472
kidney	100%	5314.57	89 / 89	97%	19.83	871 / 901
bladder	100%	7545.10	21 / 21	95%	25.36	479 / 504
adrenal gland	98%	2783.75	253 / 258	93%	14.57	215 / 230
intestine	99%	4719.77	957 / 966	92%	15.38	483 / 527
stomach	92%	3838.65	332 / 359	92%	15.07	263 / 286
ovary	86%	2817.12	154 / 180	90%	15.47	386 / 430
pancreas	56%	1168.48	184 / 328	98%	28.70	174 / 178
brain	37%	1008.16	974 / 2642	84%	11.56	595 / 705
adipose	100%	9932.11	1204 / 1204	0%	0	0 / 0
blood vessel	100%	7570.32	1335 / 1335	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	61.46	45 / 45
ureter	0%	0	0 / 0	100%	11.61	1 / 1
heart	100%	5794.69	857 / 861	0%	0	0 / 0
spleen	99%	4013.69	239 / 241	0%	0	0 / 0
eye	0%	0	0 / 0	98%	28.27	78 / 80
lymph node	0%	0	0 / 0	76%	6.42	22 / 29
muscle	74%	2205.79	593 / 803	0%	0	0 / 0
liver	18%	338.00	40 / 226	32%	3.31	131 / 406
peripheral blood	1%	20.79	12 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0007165	Biological process	signal transduction
GO_0006468	Biological process	protein phosphorylation
GO_0033554	Biological process	cellular response to stress
GO_0000165	Biological process	MAPK cascade
GO_0004709	Molecular function	MAP kinase kinase kinase activity
GO_0005524	Molecular function	ATP binding
GO_0106310	Molecular function	protein serine kinase activity
GO_0005515	Molecular function	protein binding
GO_0000287	Molecular function	magnesium ion binding

Gene name	MAP3K6
Protein name	Alternative protein MAP3K6 Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 2) Mitogen-activated protein kinase kinase kinase 6 MAP3K6 protein
Synonyms	ASK2 MAPKKK6 MEKK6
Description	FUNCTION: Component of a protein kinase signal transduction cascade. Activates the JNK, but not ERK or p38 kinase pathways. .
Accessions	ENST00000486046.5 H0Y8A3 ENST00000374040.7 [O95382-3] L8ECB4 Q32MQ5 ENST00000357582.3 [O95382-1] O95382

MAP3K6 report