MAOA report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0009967Biological processpositive regulation of signal transduction
GO_0006576Biological processbiogenic amine metabolic process
GO_0042420Biological processdopamine catabolic process
GO_0005741Cellular componentmitochondrial outer membrane
GO_0005829Cellular componentcytosol
GO_0005739Cellular componentmitochondrion
GO_0050660Molecular functionflavin adenine dinucleotide binding
GO_0005515Molecular functionprotein binding
GO_0097621Molecular functionmonoamine oxidase activity
GO_0052595Molecular functionaliphatic amine oxidase activity
GO_0008131Molecular functionprimary amine oxidase activity

IV. Literature review

[source]
Gene nameMAOA
Protein nameAmine oxidase (EC 1.4.3.-)
Amine oxidase [flavin-containing] A (EC 1.4.3.21) (EC 1.4.3.4) (Monoamine oxidase type A)
Monoamine oxidase A
Amine oxidase [flavin-containing] A (EC 1.4.3.21) (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A)
SynonymshCG_16826
DescriptionFUNCTION: Catalyzes the oxidative deamination of primary and some secondary amine such as neurotransmitters, with concomitant reduction of oxygen to hydrogen peroxide and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues . Preferentially oxidizes serotonin . Also catalyzes the oxidative deamination of kynuramine to 3-(2-aminophenyl)-3-oxopropanal that can spontaneously condense to 4-hydroxyquinoline (By similarity). .

AccessionsA0A8I5KUC3
A0A8I5KP93
Q53YE7
ENST00000689087.1 [P21397-2]
P21397
ENST00000338702.4 [P21397-1]
ENST00000542639.6 [P21397-2]
ENST00000686683.1
Q5ULA3
ENST00000688006.1 [P21397-2]
Q5UL91
Q5ULA9
ENST00000693128.1
Q49A63
Q5UL94
A0A1W5KJW8