Name | Number of supported studies | Average coverage | |
---|---|---|---|
type II pneumocyte | 11 studies | 35% ± 12% | |
basal cell | 11 studies | 26% ± 7% | |
endothelial cell | 10 studies | 27% ± 10% | |
epithelial cell | 9 studies | 33% ± 13% | |
adipocyte | 9 studies | 41% ± 11% | |
type I pneumocyte | 8 studies | 21% ± 6% | |
capillary endothelial cell | 7 studies | 26% ± 3% | |
fibroblast | 6 studies | 21% ± 5% | |
enterocyte | 6 studies | 43% ± 15% | |
club cell | 6 studies | 22% ± 4% | |
ciliated cell | 6 studies | 25% ± 11% | |
epithelial cell of proximal tubule | 5 studies | 35% ± 7% | |
transit amplifying cell | 5 studies | 27% ± 9% | |
hepatocyte | 5 studies | 35% ± 11% | |
secretory cell | 4 studies | 21% ± 5% | |
goblet cell | 4 studies | 26% ± 9% | |
intestinal crypt stem cell | 4 studies | 35% ± 6% | |
astrocyte | 4 studies | 36% ± 5% | |
smooth muscle cell | 3 studies | 20% ± 5% | |
ionocyte | 3 studies | 29% ± 12% | |
progenitor cell | 3 studies | 37% ± 14% | |
retinal cone cell | 3 studies | 30% ± 10% | |
endothelial cell of vascular tree | 3 studies | 18% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 98% | 9748.52 | 241 / 245 | 100% | 189.15 | 501 / 502 |
liver | 99% | 7310.87 | 223 / 226 | 94% | 75.29 | 383 / 406 |
thymus | 100% | 14591.46 | 652 / 653 | 93% | 199.58 | 563 / 605 |
intestine | 99% | 18342.02 | 956 / 966 | 88% | 61.62 | 465 / 527 |
lung | 99% | 14038.25 | 572 / 578 | 85% | 68.12 | 986 / 1155 |
kidney | 99% | 8489.93 | 88 / 89 | 85% | 60.96 | 768 / 901 |
bladder | 95% | 12753.76 | 20 / 21 | 85% | 80.76 | 427 / 504 |
stomach | 97% | 8979.33 | 348 / 359 | 82% | 52.25 | 234 / 286 |
esophagus | 98% | 14757.27 | 1417 / 1445 | 79% | 45.67 | 144 / 183 |
pancreas | 83% | 4255.39 | 273 / 328 | 87% | 42.95 | 154 / 178 |
uterus | 85% | 4965.93 | 145 / 170 | 61% | 36.29 | 278 / 459 |
brain | 62% | 2449.73 | 1643 / 2642 | 77% | 27.86 | 546 / 705 |
adrenal gland | 81% | 5247.12 | 210 / 258 | 48% | 25.24 | 110 / 230 |
breast | 95% | 14496.07 | 436 / 459 | 30% | 13.56 | 333 / 1118 |
ureter | 0% | 0 | 0 / 0 | 100% | 39.03 | 1 / 1 |
adipose | 100% | 18372.85 | 1203 / 1204 | 0% | 0 | 0 / 0 |
ovary | 92% | 7405.93 | 166 / 180 | 6% | 1.62 | 27 / 430 |
blood vessel | 98% | 12750.95 | 1308 / 1335 | 0% | 0 | 0 / 0 |
skin | 90% | 6858.14 | 1628 / 1809 | 6% | 1.43 | 29 / 472 |
heart | 82% | 6012.95 | 710 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 78% | 50.35 | 35 / 45 |
muscle | 49% | 3680.15 | 397 / 803 | 0% | 0 | 0 / 0 |
spleen | 18% | 548.41 | 44 / 241 | 0% | 0 | 0 / 0 |
peripheral blood | 9% | 347.31 | 82 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 3% | 0.89 | 1 / 29 |
eye | 0% | 0 | 0 / 0 | 1% | 0.20 | 1 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0009967 | Biological process | positive regulation of signal transduction |
GO_0006576 | Biological process | biogenic amine metabolic process |
GO_0042420 | Biological process | dopamine catabolic process |
GO_0005741 | Cellular component | mitochondrial outer membrane |
GO_0005829 | Cellular component | cytosol |
GO_0005739 | Cellular component | mitochondrion |
GO_0050660 | Molecular function | flavin adenine dinucleotide binding |
GO_0005515 | Molecular function | protein binding |
GO_0097621 | Molecular function | monoamine oxidase activity |
GO_0052595 | Molecular function | aliphatic amine oxidase activity |
GO_0008131 | Molecular function | primary amine oxidase activity |
Gene name | MAOA |
Protein name | Amine oxidase (EC 1.4.3.-) Amine oxidase [flavin-containing] A (EC 1.4.3.21) (EC 1.4.3.4) (Monoamine oxidase type A) Monoamine oxidase A Amine oxidase [flavin-containing] A (EC 1.4.3.21) (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A) |
Synonyms | hCG_16826 |
Description | FUNCTION: Catalyzes the oxidative deamination of primary and some secondary amine such as neurotransmitters, with concomitant reduction of oxygen to hydrogen peroxide and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues . Preferentially oxidizes serotonin . Also catalyzes the oxidative deamination of kynuramine to 3-(2-aminophenyl)-3-oxopropanal that can spontaneously condense to 4-hydroxyquinoline (By similarity). . |
Accessions | A0A8I5KUC3 A0A8I5KP93 Q53YE7 ENST00000689087.1 [P21397-2] P21397 ENST00000338702.4 [P21397-1] ENST00000542639.6 [P21397-2] ENST00000686683.1 Q5ULA3 ENST00000688006.1 [P21397-2] Q5UL91 Q5ULA9 ENST00000693128.1 Q49A63 Q5UL94 A0A1W5KJW8 |