Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| classical monocyte | 8 studies | 24% ± 10% |
Insufficient scRNA-seq data for expression of LTB4R at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 95% | 1611.76 | 435 / 459 | 90% | 8.49 | 1002 / 1118 |
| lung | 97% | 2141.22 | 562 / 578 | 84% | 16.63 | 975 / 1155 |
| thymus | 92% | 1452.24 | 600 / 653 | 71% | 18.16 | 428 / 605 |
| skin | 81% | 8946.81 | 1461 / 1809 | 80% | 8.75 | 377 / 472 |
| prostate | 91% | 2227.36 | 223 / 245 | 64% | 4.01 | 321 / 502 |
| adrenal gland | 77% | 1169.54 | 199 / 258 | 73% | 6.39 | 169 / 230 |
| uterus | 54% | 763.07 | 91 / 170 | 93% | 29.79 | 427 / 459 |
| esophagus | 50% | 4587.05 | 720 / 1445 | 97% | 37.00 | 177 / 183 |
| ovary | 73% | 888.94 | 132 / 180 | 62% | 4.68 | 268 / 430 |
| kidney | 54% | 862.75 | 48 / 89 | 79% | 7.54 | 714 / 901 |
| bladder | 48% | 528.76 | 10 / 21 | 81% | 10.35 | 409 / 504 |
| liver | 68% | 935.42 | 153 / 226 | 56% | 4.08 | 226 / 406 |
| intestine | 43% | 653.57 | 417 / 966 | 73% | 5.64 | 384 / 527 |
| pancreas | 20% | 251.11 | 65 / 328 | 89% | 7.87 | 158 / 178 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 12.12 | 29 / 29 |
| spleen | 100% | 5272.07 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 46.88 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 5.79 | 1 / 1 |
| peripheral blood | 98% | 7614.60 | 911 / 929 | 0% | 0 | 0 / 0 |
| adipose | 94% | 1625.63 | 1133 / 1204 | 0% | 0 | 0 / 0 |
| stomach | 24% | 263.47 | 85 / 359 | 63% | 4.37 | 179 / 286 |
| brain | 5% | 50.45 | 130 / 2642 | 62% | 3.95 | 435 / 705 |
| eye | 0% | 0 | 0 / 0 | 30% | 1.78 | 24 / 80 |
| blood vessel | 20% | 265.36 | 266 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 16% | 213.91 | 125 / 803 | 0% | 0 | 0 / 0 |
| heart | 5% | 62.93 | 45 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006955 | Biological process | immune response |
| GO_0061737 | Biological process | leukotriene signaling pathway |
| GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
| GO_0007218 | Biological process | neuropeptide signaling pathway |
| GO_0006954 | Biological process | inflammatory response |
| GO_0007200 | Biological process | phospholipase C-activating G protein-coupled receptor signaling pathway |
| GO_0006936 | Biological process | muscle contraction |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0004974 | Molecular function | leukotriene receptor activity |
| GO_0008528 | Molecular function | G protein-coupled peptide receptor activity |
| GO_0001632 | Molecular function | leukotriene B4 receptor activity |
| GO_0000166 | Molecular function | nucleotide binding |
| Gene name | LTB4R |
| Protein name | Leukotriene B4 receptor Leukotriene B4 receptor 1 (LTB4-R 1) (LTB4-R1) (Chemoattractant receptor-like 1) (G-protein coupled receptor 16) (P2Y purinoceptor 7) (P2Y7) |
| Synonyms | BLT CMKRL1 BLT1 P2RY7 BLTR GPR16 |
| Description | FUNCTION: Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response. |
| Accessions | ENST00000553481.1 ENST00000345363.8 G3V4Q5 G3V244 ENST00000556141.1 ENST00000396782.2 ENST00000647085.2 ENST00000646739.1 ENST00000646659.1 Q15722 ENST00000396789.4 |