LRRC15 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of LRRC15 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of LRRC15 at tissue level.

III. Associated gene sets

GO_0046813Biological processreceptor-mediated virion attachment to host cell
GO_0030335Biological processpositive regulation of cell migration
GO_0046597Biological processnegative regulation of viral entry into host cell
GO_1903077Biological processnegative regulation of protein localization to plasma membrane
GO_0016324Cellular componentapical plasma membrane
GO_0005615Cellular componentextracellular space
GO_0070062Cellular componentextracellular exosome
GO_0062023Cellular componentcollagen-containing extracellular matrix
GO_0005886Cellular componentplasma membrane
GO_0031012Cellular componentextracellular matrix
GO_0043236Molecular functionlaminin binding
GO_0140311Molecular functionprotein sequestering activity
GO_0005518Molecular functioncollagen binding
GO_0001968Molecular functionfibronectin binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameLRRC15
Protein nameLeucine-rich repeat-containing protein 15 (Leucine-rich repeat protein induced by beta-amyloid homolog) (hLib)
SynonymsLIB
DescriptionFUNCTION: (Microbial infection) Modulates the ability of SARS-CoV-2 to infect host cells through interaction with the spike protein . Does not act as a SARS-CoV-2 entry receptor but sequesters virions and antagonizes in trans SARS-CoV-2 infection of ACE2(+) cells when expressed on nearby cells . .

AccessionsQ8TF66
ENST00000347624.4 [Q8TF66-1]
ENST00000428839.1 [Q8TF66-2]