I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| astrocyte | 10 studies | 37% ± 13% | |
| Mueller cell | 5 studies | 33% ± 12% | |
| retinal pigment epithelial cell | 3 studies | 29% ± 14% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| astrocyte | 10 studies | 37% ± 13% | |
| Mueller cell | 5 studies | 33% ± 12% | |
| retinal pigment epithelial cell | 3 studies | 29% ± 14% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 22% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 68% | 2263.57 | 1808 / 2642 | 99% | 29.66 | 700 / 705 |
| tonsil | 0% | 0 | 0 / 0 | 82% | 8.27 | 37 / 45 |
| skin | 26% | 187.59 | 476 / 1809 | 54% | 6.13 | 253 / 472 |
| uterus | 0% | 0 | 0 / 170 | 57% | 7.86 | 263 / 459 |
| liver | 43% | 156.95 | 97 / 226 | 11% | 0.83 | 46 / 406 |
| eye | 0% | 0 | 0 / 0 | 36% | 2.62 | 29 / 80 |
| esophagus | 0% | 0 | 0 / 1445 | 33% | 3.57 | 60 / 183 |
| lymph node | 0% | 0 | 0 / 0 | 24% | 2.04 | 7 / 29 |
| lung | 0% | 0 | 0 / 578 | 21% | 1.75 | 245 / 1155 |
| ovary | 1% | 3.54 | 2 / 180 | 12% | 1.72 | 53 / 430 |
| bladder | 0% | 0 | 0 / 21 | 12% | 0.74 | 58 / 504 |
| breast | 0% | 0 | 0 / 459 | 11% | 0.77 | 128 / 1118 |
| adrenal gland | 0% | 0 | 0 / 258 | 9% | 0.51 | 20 / 230 |
| peripheral blood | 5% | 33.88 | 42 / 929 | 0% | 0 | 0 / 0 |
| stomach | 0% | 0 | 0 / 359 | 4% | 0.24 | 11 / 286 |
| thymus | 0% | 0 | 0 / 653 | 3% | 2.40 | 21 / 605 |
| pancreas | 0% | 0 | 0 / 328 | 3% | 0.50 | 5 / 178 |
| kidney | 0% | 0 | 0 / 89 | 2% | 0.43 | 22 / 901 |
| intestine | 0% | 0 | 0 / 966 | 2% | 0.08 | 8 / 527 |
| prostate | 0% | 0 | 0 / 245 | 1% | 0.03 | 4 / 502 |
| adipose | 0% | 0.70 | 3 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 0.46 | 1 / 1335 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0045814 | Biological process | negative regulation of gene expression, epigenetic |
| GO_0007498 | Biological process | mesoderm development |
| GO_0045199 | Biological process | maintenance of epithelial cell apical/basal polarity |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0021978 | Biological process | telencephalon regionalization |
| GO_0060041 | Biological process | retina development in camera-type eye |
| GO_0021772 | Biological process | olfactory bulb development |
| GO_0009953 | Biological process | dorsal/ventral pattern formation |
| GO_0030182 | Biological process | neuron differentiation |
| GO_2000179 | Biological process | positive regulation of neural precursor cell proliferation |
| GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
| GO_0001843 | Biological process | neural tube closure |
| GO_0001942 | Biological process | hair follicle development |
| GO_0048675 | Biological process | axon extension |
| GO_0021987 | Biological process | cerebral cortex development |
| GO_0050768 | Biological process | negative regulation of neurogenesis |
| GO_0007411 | Biological process | axon guidance |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_0000785 | Cellular component | chromatin |
| GO_0005634 | Cellular component | nucleus |
| GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO_0000977 | Molecular function | RNA polymerase II transcription regulatory region sequence-specific DNA binding |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO_0003682 | Molecular function | chromatin binding |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | LHX2 |
| Protein name | LIM homeobox 2 LIM/homeobox protein Lhx2 (Homeobox protein LH-2) (LIM homeobox protein 2) |
| Synonyms | LH2 |
| Description | FUNCTION: Acts as a transcriptional activator. Stimulates the promoter of the alpha-glycoprotein gene. Transcriptional regulatory protein involved in the control of cell differentiation in developing lymphoid and neural cell types (By similarity). . |
| Accessions | ENST00000560961.2 ENST00000446480.5 U3KQT5 ENST00000488674.2 H0YM35 ENST00000373615.9 P50458 H7C0H1 |
