LEUTX report

I. Expression across cell types

Insufficient scRNA-seq data for expression of LEUTX at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of LEUTX at tissue level.

III. Associated gene sets

GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0005654Cellular componentnucleoplasm
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene nameLEUTX
Protein namePaired-like homeodomain transcription factor LEUTX (Leucine-twenty homeobox) (Paired-like homeobox transcription factor LEUTX) (PRD-LIKE homeobox transcription factor LEUTX)
Synonyms
DescriptionFUNCTION: [Isoform 1]: Paired-like homeobox transcription factor involved in embryogenesis . May act as a regulator of embryo genome activation . Binds to a 36 bp DNA elements containing a 5'-TAATCC-3' sequence motif, referred to as EEA motif (EGA-enriched Alu-motif), present in the promoters of target genes activated in early embryos . .; FUNCTION: [Isoform 2]: Inactive transcriptional activity. .

AccessionsENST00000629267.1 [A8MZ59-1]
ENST00000638280.2 [A8MZ59-2]
A8MZ59
ENST00000396841.4 [A8MZ59-1]
ENST00000640845.1 [A8MZ59-2]