Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 10 studies | 25% ± 11% | |
| microglial cell | 7 studies | 23% ± 7% | |
| interneuron | 6 studies | 30% ± 20% | |
| oligodendrocyte precursor cell | 6 studies | 29% ± 13% | |
| GABAergic neuron | 6 studies | 36% ± 18% | |
| astrocyte | 6 studies | 28% ± 12% | |
| epithelial cell | 5 studies | 28% ± 9% | |
| oligodendrocyte | 5 studies | 25% ± 8% | |
| macrophage | 4 studies | 23% ± 5% | |
| ciliated cell | 3 studies | 20% ± 1% | |
| glutamatergic neuron | 3 studies | 62% ± 2% | |
| endothelial cell of lymphatic vessel | 3 studies | 20% ± 5% | |
| plasmacytoid dendritic cell | 3 studies | 22% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 6 studies | 38% ± 15% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 1634.90 | 1445 / 1445 | 100% | 26.26 | 183 / 183 |
| lung | 100% | 1973.76 | 578 / 578 | 100% | 22.77 | 1155 / 1155 |
| brain | 100% | 1576.57 | 2639 / 2642 | 100% | 21.12 | 705 / 705 |
| breast | 100% | 2064.11 | 459 / 459 | 100% | 24.71 | 1116 / 1118 |
| prostate | 100% | 1553.58 | 245 / 245 | 100% | 19.98 | 501 / 502 |
| ovary | 100% | 2146.29 | 180 / 180 | 100% | 16.33 | 429 / 430 |
| stomach | 100% | 1484.45 | 359 / 359 | 100% | 21.44 | 285 / 286 |
| intestine | 100% | 1821.50 | 966 / 966 | 99% | 21.33 | 523 / 527 |
| thymus | 100% | 1923.34 | 653 / 653 | 99% | 19.18 | 600 / 605 |
| pancreas | 100% | 1150.71 | 328 / 328 | 99% | 16.40 | 176 / 178 |
| bladder | 100% | 1740.71 | 21 / 21 | 99% | 18.47 | 498 / 504 |
| adrenal gland | 100% | 1462.72 | 258 / 258 | 99% | 15.19 | 227 / 230 |
| uterus | 100% | 2423.18 | 170 / 170 | 99% | 21.57 | 453 / 459 |
| kidney | 100% | 1074.36 | 89 / 89 | 98% | 19.42 | 886 / 901 |
| skin | 100% | 1891.00 | 1809 / 1809 | 95% | 17.47 | 449 / 472 |
| liver | 100% | 879.69 | 226 / 226 | 81% | 7.58 | 328 / 406 |
| adipose | 100% | 1941.25 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1887.17 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 15.23 | 29 / 29 |
| spleen | 100% | 2069.82 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 25.55 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 6.36 | 1 / 1 |
| muscle | 100% | 1187.49 | 802 / 803 | 0% | 0 | 0 / 0 |
| heart | 99% | 992.07 | 851 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 80% | 9.05 | 64 / 80 |
| peripheral blood | 78% | 1023.40 | 727 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0030514 | Biological process | negative regulation of BMP signaling pathway |
| GO_0030512 | Biological process | negative regulation of transforming growth factor beta receptor signaling pathway |
| GO_0032926 | Biological process | negative regulation of activin receptor signaling pathway |
| GO_0031965 | Cellular component | nuclear membrane |
| GO_0005637 | Cellular component | nuclear inner membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0003677 | Molecular function | DNA binding |
| GO_0005515 | Molecular function | protein binding |
| GO_1990446 | Molecular function | U1 snRNP binding |
| Gene name | LEMD3 |
| Protein name | Inner nuclear membrane protein Man1 (LEM domain-containing protein 3) |
| Synonyms | MAN1 |
| Description | FUNCTION: Can function as a specific repressor of TGF-beta, activin, and BMP signaling through its interaction with the R-SMAD proteins. Antagonizes TGF-beta-induced cell proliferation arrest. . |
| Accessions | ENST00000308330.3 Q9Y2U8 |