LAMB2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of LAMB2 at tissue level.

III. Associated gene sets

GO_0007601Biological processvisual perception
GO_0072249Biological processmetanephric podocyte development
GO_0051149Biological processpositive regulation of muscle cell differentiation
GO_2001046Biological processpositive regulation of integrin-mediated signaling pathway
GO_0007155Biological processcell adhesion
GO_0060041Biological processretina development in camera-type eye
GO_0045785Biological processpositive regulation of cell adhesion
GO_0007528Biological processneuromuscular junction development
GO_0014044Biological processSchwann cell development
GO_0014002Biological processastrocyte development
GO_0072274Biological processmetanephric glomerular basement membrane development
GO_0110011Biological processregulation of basement membrane organization
GO_0048677Biological processaxon extension involved in regeneration
GO_0007411Biological processaxon guidance
GO_0005576Cellular componentextracellular region
GO_0031594Cellular componentneuromuscular junction
GO_0070062Cellular componentextracellular exosome
GO_0062023Cellular componentcollagen-containing extracellular matrix
GO_0005788Cellular componentendoplasmic reticulum lumen
GO_0043260Cellular componentlaminin-11 complex
GO_0098637Cellular componentprotein complex involved in cell-matrix adhesion
GO_0043083Cellular componentsynaptic cleft
GO_0005604Cellular componentbasement membrane
GO_0005608Cellular componentlaminin-3 complex
GO_0005201Molecular functionextracellular matrix structural constituent
GO_0005198Molecular functionstructural molecule activity
GO_0005178Molecular functionintegrin binding
GO_0150043Molecular functionstructural constituent of synapse-associated extracellular matrix
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameLAMB2
Protein nameLaminin subunit beta 2
Laminin subunit beta-2 (Laminin B1s chain) (Laminin-11 subunit beta) (Laminin-14 subunit beta) (Laminin-15 subunit beta) (Laminin-3 subunit beta) (Laminin-4 subunit beta) (Laminin-7 subunit beta) (Laminin-9 subunit beta) (S-laminin subunit beta) (S-LAM beta)
SynonymsLAMS
DescriptionFUNCTION: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.

AccessionsENST00000494831.1
F5H520
ENST00000418109.5
ENST00000305544.9
P55268