Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| natural killer cell | 10 studies | 22% ± 6% | |
| CD16-negative, CD56-bright natural killer cell, human | 8 studies | 29% ± 6% | |
| CD16-positive, CD56-dim natural killer cell, human | 8 studies | 23% ± 6% | |
| mature NK T cell | 6 studies | 30% ± 14% | |
| gamma-delta T cell | 6 studies | 26% ± 8% | |
| oligodendrocyte precursor cell | 5 studies | 29% ± 11% |
Insufficient scRNA-seq data for expression of KLRC3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 97% | 116.45 | 2574 / 2642 | 69% | 3.76 | 488 / 705 |
| spleen | 100% | 160.70 | 241 / 241 | 0% | 0 | 0 / 0 |
| lung | 92% | 50.28 | 529 / 578 | 2% | 0.04 | 26 / 1155 |
| peripheral blood | 68% | 100.19 | 629 / 929 | 0% | 0 | 0 / 0 |
| stomach | 55% | 14.20 | 199 / 359 | 1% | 0.02 | 4 / 286 |
| thymus | 47% | 12.82 | 309 / 653 | 1% | 0.01 | 4 / 605 |
| adipose | 47% | 14.06 | 562 / 1204 | 0% | 0 | 0 / 0 |
| prostate | 45% | 9.84 | 110 / 245 | 0% | 0.00 | 1 / 502 |
| intestine | 45% | 18.65 | 433 / 966 | 0% | 0.00 | 1 / 527 |
| breast | 39% | 10.85 | 178 / 459 | 2% | 0.04 | 21 / 1118 |
| bladder | 38% | 11.24 | 8 / 21 | 1% | 0.01 | 4 / 504 |
| liver | 37% | 7.81 | 84 / 226 | 0% | 0 | 0 / 406 |
| uterus | 26% | 5.09 | 45 / 170 | 1% | 0.02 | 5 / 459 |
| kidney | 20% | 3.98 | 18 / 89 | 0% | 0.00 | 1 / 901 |
| ovary | 17% | 3.81 | 31 / 180 | 0% | 0 | 0 / 430 |
| blood vessel | 16% | 3.53 | 216 / 1335 | 0% | 0 | 0 / 0 |
| esophagus | 16% | 2.93 | 226 / 1445 | 0% | 0 | 0 / 183 |
| skin | 7% | 1.19 | 122 / 1809 | 5% | 0.08 | 22 / 472 |
| heart | 7% | 1.18 | 60 / 861 | 0% | 0 | 0 / 0 |
| pancreas | 5% | 0.87 | 17 / 328 | 1% | 0.02 | 2 / 178 |
| adrenal gland | 3% | 0.59 | 8 / 258 | 0% | 0.00 | 1 / 230 |
| muscle | 1% | 0.19 | 7 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006968 | Biological process | cellular defense response |
| GO_0045954 | Biological process | positive regulation of natural killer cell mediated cytotoxicity |
| GO_0032814 | Biological process | regulation of natural killer cell activation |
| GO_0002223 | Biological process | stimulatory C-type lectin receptor signaling pathway |
| GO_0009897 | Cellular component | external side of plasma membrane |
| GO_0043235 | Cellular component | receptor complex |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0004888 | Molecular function | transmembrane signaling receptor activity |
| GO_0030246 | Molecular function | carbohydrate binding |
| Gene name | KLRC3 |
| Protein name | NKG2-E type II integral membrane protein (NK cell receptor E) (NKG2-E-activating NK receptor) |
| Synonyms | NKG2E |
| Description | FUNCTION: Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. |
| Accessions | ENST00000396439.7 [Q07444-1] ENST00000381903.2 [Q07444-2] Q07444 |
