Insufficient scRNA-seq data for expression of KLF17 at single-cell level.
Insufficient scRNA-seq data for expression of KLF17 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
adrenal gland | 99% | 85.79 | 255 / 258 | 15% | 0.61 | 35 / 230 |
lung | 98% | 80.16 | 569 / 578 | 2% | 0.04 | 26 / 1155 |
uterus | 87% | 81.10 | 148 / 170 | 4% | 0.10 | 19 / 459 |
bladder | 76% | 172.43 | 16 / 21 | 4% | 0.08 | 18 / 504 |
esophagus | 73% | 94.75 | 1053 / 1445 | 4% | 0.08 | 7 / 183 |
brain | 43% | 8.18 | 1137 / 2642 | 9% | 0.16 | 61 / 705 |
intestine | 50% | 31.12 | 483 / 966 | 2% | 0.03 | 8 / 527 |
stomach | 31% | 12.24 | 113 / 359 | 3% | 0.06 | 9 / 286 |
prostate | 34% | 12.22 | 83 / 245 | 0% | 0 | 0 / 502 |
skin | 16% | 5.96 | 288 / 1809 | 13% | 0.26 | 62 / 472 |
blood vessel | 24% | 7.46 | 322 / 1335 | 0% | 0 | 0 / 0 |
breast | 5% | 1.62 | 24 / 459 | 7% | 0.21 | 81 / 1118 |
ovary | 8% | 1.81 | 14 / 180 | 0% | 0.00 | 1 / 430 |
adipose | 8% | 2.30 | 94 / 1204 | 0% | 0 | 0 / 0 |
spleen | 3% | 0.47 | 8 / 241 | 0% | 0 | 0 / 0 |
heart | 3% | 0.65 | 25 / 861 | 0% | 0 | 0 / 0 |
pancreas | 2% | 0.38 | 7 / 328 | 0% | 0 | 0 / 178 |
liver | 0% | 0.18 | 1 / 226 | 1% | 0.03 | 3 / 406 |
thymus | 1% | 0.32 | 6 / 653 | 0% | 0 | 0 / 605 |
kidney | 0% | 0 | 0 / 89 | 1% | 0.02 | 7 / 901 |
muscle | 0% | 0.27 | 4 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0.03 | 2 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0000785 | Cellular component | chromatin |
GO_0005634 | Cellular component | nucleus |
GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0003700 | Molecular function | DNA-binding transcription factor activity |
GO_0005515 | Molecular function | protein binding |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
GO_0046872 | Molecular function | metal ion binding |
GO_0000976 | Molecular function | transcription cis-regulatory region binding |
Gene name | KLF17 |
Protein name | KLF transcription factor 17 Krueppel-like factor 17 (Zinc finger protein 393) |
Synonyms | ZNF393 |
Description | FUNCTION: Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development (By similarity). . |
Accessions | Q5JT82 ENST00000372299.4 A0A0U1RR65 ENST00000476802.1 |