KIF5A report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1990049Biological processretrograde neuronal dense core vesicle transport
GO_0016192Biological processvesicle-mediated transport
GO_0007268Biological processchemical synaptic transmission
GO_0007018Biological processmicrotubule-based movement
GO_0098971Biological processanterograde dendritic transport of neurotransmitter receptor complex
GO_0007411Biological processaxon guidance
GO_0099641Biological processanterograde axonal protein transport
GO_0048489Biological processsynaptic vesicle transport
GO_0005874Cellular componentmicrotubule
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0016020Cellular componentmembrane
GO_0043204Cellular componentperikaryon
GO_0005871Cellular componentkinesin complex
GO_0035253Cellular componentciliary rootlet
GO_0005829Cellular componentcytosol
GO_0045202Cellular componentsynapse
GO_0032839Cellular componentdendrite cytoplasm
GO_1904115Cellular componentaxon cytoplasm
GO_0008574Molecular functionplus-end-directed microtubule motor activity
GO_0003774Molecular functioncytoskeletal motor activity
GO_0019894Molecular functionkinesin binding
GO_0008017Molecular functionmicrotubule binding
GO_0005524Molecular functionATP binding
GO_0005515Molecular functionprotein binding
GO_0016887Molecular functionATP hydrolysis activity

IV. Literature review

[source]
Gene nameKIF5A
Protein nameKinesin family member 5A
Kinesin heavy chain isoform 5A (Kinesin heavy chain neuron-specific 1) (Neuronal kinesin heavy chain) (NKHC)
Kinesin-like protein
SynonymsNKHC1
DescriptionFUNCTION: Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL). Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. The ZFYVE27-KIF5A complex contributes to the vesicular transport of VAPA, VAPB, SURF4, RAB11A, RAB11B and RTN3 proteins in neurons. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation. .

AccessionsENST00000455537.7
A0A6Q8PGJ3
A0A6Q8PGG7
A0A6Q8PFR6
ENST00000676457.1
A0A6Q8PFG5
Q12840
A0A6Q8PH74
A0A6Q8PH72
A0A6Q8PFV6
ENST00000676250.1
ENST00000675697.1
ENST00000675629.1
ENST00000675866.1
ENST00000674980.1
A0A6Q8PFQ3
ENST00000674619.1
A0A6Q8PGN1
ENST00000675634.1
ENST00000674858.1
A0A6Q8PFB8
ENST00000676352.1
A0A6Q8PHA9
ENST00000286452.5
ENST00000675299.1
A0A6Q8PGP0
A0A6Q8PGT2
ENST00000676437.1
ENST00000675023.1
J3KNA1
ENST00000675216.1
ENST00000674776.1
ENST00000675433.1
A0A6Q8PFD6
A0A6Q8PGP8
ENST00000676359.1
A0A6Q8PH22
A5D6Y6
ENST00000675907.1
ENST00000676055.1
A0A6Q8PEZ8