Name | Number of supported studies | Average coverage | |
---|---|---|---|
glutamatergic neuron | 11 studies | 40% ± 16% | |
neuron | 7 studies | 33% ± 9% | |
GABAergic neuron | 7 studies | 41% ± 12% | |
interneuron | 6 studies | 38% ± 20% | |
retinal ganglion cell | 6 studies | 63% ± 24% | |
GABAergic interneuron | 3 studies | 28% ± 10% | |
granule cell | 3 studies | 23% ± 5% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 12 studies | 27% ± 12% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 91376.01 | 2638 / 2642 | 100% | 100.30 | 703 / 705 |
adrenal gland | 2% | 94.61 | 5 / 258 | 67% | 23.36 | 155 / 230 |
ovary | 0% | 0 | 0 / 180 | 55% | 1.85 | 237 / 430 |
pancreas | 0% | 0 | 0 / 328 | 46% | 1.68 | 81 / 178 |
thymus | 0% | 14.14 | 2 / 653 | 31% | 1.34 | 185 / 605 |
breast | 0% | 8.28 | 1 / 459 | 20% | 0.62 | 221 / 1118 |
uterus | 1% | 24.09 | 1 / 170 | 17% | 0.61 | 79 / 459 |
lymph node | 0% | 0 | 0 / 0 | 17% | 0.39 | 5 / 29 |
stomach | 0% | 0 | 0 / 359 | 16% | 0.31 | 46 / 286 |
lung | 0% | 0 | 0 / 578 | 16% | 0.44 | 183 / 1155 |
bladder | 0% | 0 | 0 / 21 | 14% | 0.44 | 71 / 504 |
intestine | 2% | 74.47 | 16 / 966 | 11% | 0.26 | 60 / 527 |
skin | 0% | 1.96 | 1 / 1809 | 12% | 0.43 | 58 / 472 |
esophagus | 0% | 5.72 | 2 / 1445 | 10% | 0.29 | 19 / 183 |
kidney | 0% | 0 | 0 / 89 | 5% | 0.14 | 49 / 901 |
eye | 0% | 0 | 0 / 0 | 5% | 0.70 | 4 / 80 |
tonsil | 0% | 0 | 0 / 0 | 4% | 0.19 | 2 / 45 |
prostate | 0% | 0 | 0 / 245 | 2% | 0.08 | 12 / 502 |
liver | 0% | 0 | 0 / 226 | 2% | 0.04 | 8 / 406 |
heart | 0% | 15.17 | 2 / 861 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
adipose | 0% | 0 | 0 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 0% | 0 | 0 / 1335 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_1990049 | Biological process | retrograde neuronal dense core vesicle transport |
GO_0016192 | Biological process | vesicle-mediated transport |
GO_0007268 | Biological process | chemical synaptic transmission |
GO_0007018 | Biological process | microtubule-based movement |
GO_0098971 | Biological process | anterograde dendritic transport of neurotransmitter receptor complex |
GO_0007411 | Biological process | axon guidance |
GO_0099641 | Biological process | anterograde axonal protein transport |
GO_0048489 | Biological process | synaptic vesicle transport |
GO_0005874 | Cellular component | microtubule |
GO_0048471 | Cellular component | perinuclear region of cytoplasm |
GO_0016020 | Cellular component | membrane |
GO_0043204 | Cellular component | perikaryon |
GO_0005871 | Cellular component | kinesin complex |
GO_0035253 | Cellular component | ciliary rootlet |
GO_0005829 | Cellular component | cytosol |
GO_0045202 | Cellular component | synapse |
GO_0032839 | Cellular component | dendrite cytoplasm |
GO_1904115 | Cellular component | axon cytoplasm |
GO_0008574 | Molecular function | plus-end-directed microtubule motor activity |
GO_0003774 | Molecular function | cytoskeletal motor activity |
GO_0019894 | Molecular function | kinesin binding |
GO_0008017 | Molecular function | microtubule binding |
GO_0005524 | Molecular function | ATP binding |
GO_0005515 | Molecular function | protein binding |
GO_0016887 | Molecular function | ATP hydrolysis activity |
Gene name | KIF5A |
Protein name | Kinesin family member 5A Kinesin heavy chain isoform 5A (Kinesin heavy chain neuron-specific 1) (Neuronal kinesin heavy chain) (NKHC) Kinesin-like protein |
Synonyms | NKHC1 |
Description | FUNCTION: Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL). Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. The ZFYVE27-KIF5A complex contributes to the vesicular transport of VAPA, VAPB, SURF4, RAB11A, RAB11B and RTN3 proteins in neurons. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation. . |
Accessions | ENST00000455537.7 A0A6Q8PGJ3 A0A6Q8PGG7 A0A6Q8PFR6 ENST00000676457.1 A0A6Q8PFG5 Q12840 A0A6Q8PH74 A0A6Q8PH72 A0A6Q8PFV6 ENST00000676250.1 ENST00000675697.1 ENST00000675629.1 ENST00000675866.1 ENST00000674980.1 A0A6Q8PFQ3 ENST00000674619.1 A0A6Q8PGN1 ENST00000675634.1 ENST00000674858.1 A0A6Q8PFB8 ENST00000676352.1 A0A6Q8PHA9 ENST00000286452.5 ENST00000675299.1 A0A6Q8PGP0 A0A6Q8PGT2 ENST00000676437.1 ENST00000675023.1 J3KNA1 ENST00000675216.1 ENST00000674776.1 ENST00000675433.1 A0A6Q8PFD6 A0A6Q8PGP8 ENST00000676359.1 A0A6Q8PH22 A5D6Y6 ENST00000675907.1 ENST00000676055.1 A0A6Q8PEZ8 |